| Tag | Content |
|---|---|
| Uniprot ID | A0A287BFQ6 |
| Entrez ID | |
| Genbank protein ID | HDB37326.1 |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000054961 |
| Ensembl nucleotide ID | ENSSSCG00000017265 |
| Gene name | Axin-2 |
| Gene symbol | AXIN2 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSSAVLVPRL PDPSSSFHED APRPPVPGEE GETPPCQPGL GKGQVTKPMP VSSNTRRNED 60 GLGEPEGRAS PDSPLTRWTK SLHSLLGDQD GAYLFRTFLE REKCVDTLDF WFACNGFRQM 120 NLKETKTLRV AKAIYKRYIE NNSVVSKQLK PATKTYIRDG IKKQQIDSIM FDQAQTEIQS 180 VMEDNAYQMF LTSDIYLEYV RSGGENTAYM SNGGLGSLKL VCGYLPTLNE EEEWTCADFK 240 CKLSPTVVGL SSKTLRATAN VRSTETVENG YRSFKRSDPV NPYHVGSGYV FAPATSANDS 300 EISSDAMTDD SMSMTDSSVD GIPPYRVGSK KQLQREMHRS VKANGQVSLP HFPRTHRLPK 360 EMTPVEPATF AAELISRLEK LKLELETRHS LEERLQQIRE DEEKEGTELA TLSSREVGPA 420 QHPLSLLPSG TYEEDPQTIL DDHLSRVLKT PGCQSPGMGR YSPRARSPDH HHHHHHQPYH 480 PLLPPGGKLP AAAAASPAGC PLLGAKGFVT KQTTKHVHHH YIHHHAIPKT KEEIEAEATQ 540 RVRCFCPGGA EYYCYSKCKS HPKSPEPVAP EQFGGSTPPR RNAKGTEPGP ALPAREGGAP 600 GGAGALQLPG EEGDRSQDVW QWVLESERPS KPKPHSAQST KRAYPLESAR PSPAERAGRH 660 HLWGGSNGHP RTAPRAHPFT QDPAMPPLTP PNTLAQLEEA CRRLAEVSKP PKQRCCVASQ 720 QRDRNHSATG QTGATPFSNP SLASEDHKEP KKLAGVHTLQ ASELVVTYFF CGEEIPYRRM 780 LKAQSLTLGH FKEQLSKKGN YRYYFKTASD EFACGAVFEE IWDDEMVLPM YEGRILGKVE 840 RID 843 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | AXIN2 | 490903 | E2R9F8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | AXIN2 | 102180348 | A0A452FEH8 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | AXIN2 | 8313 | Q9Y2T1 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Axin2 | 12006 | O88566 | E13.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | AXIN2 | 468301 | A0A2I3SZU8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | AXIN2 | A0A287BFQ6 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Axin2 | A0A0G2K4L4 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | axin2 | 58080 | P57095 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005813 | centrosome |
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0070411 | I-SMAD binding |
| GO:0031625 | ubiquitin protein ligase binding |
| GO:0030282 | bone mineralization |
| GO:0008283 | cell population proliferation |
| GO:0034613 | cellular protein localization |
| GO:0003413 | chondrocyte differentiation involved in endochondral bone morphogenesis |
| GO:0001957 | intramembranous ossification |
| GO:0043570 | maintenance of DNA repeat elements |
| GO:0048255 | mRNA stabilization |
| GO:0090090 | negative regulation of canonical Wnt signaling pathway |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0045668 | negative regulation of osteoblast differentiation |
| GO:0042476 | odontogenesis |
| GO:0010942 | positive regulation of cell death |
| GO:0010718 | positive regulation of epithelial to mesenchymal transition |
| GO:0001934 | positive regulation of protein phosphorylation |
| GO:0070602 | regulation of centromeric sister chromatid cohesion |
| GO:0061181 | regulation of chondrocyte development |
| GO:0032423 | regulation of mismatch repair |
| GO:0003139 | secondary heart field specification |
| GO:0001756 | somitogenesis |
| GO:0016055 | Wnt signaling pathway |