Gene: AXIN2

Basic information

Tag Content
Uniprot ID A0A2I3SZU8
Entrez ID 468301
Genbank protein ID
Genbank nucleotide ID XM_016932770.1
Ensembl protein ID ENSPTRP00000082128
Ensembl nucleotide ID ENSPTRG00000009554
Gene name Axin 2
Gene symbol AXIN2
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSSAMLVTCL PDPSSSFRED APRPPVPGEE GETPPCQPGV GKGQVTKPMP VSSNTRRNED 60
GLGEPEGRAS PDSPLTRWTK SLHSLLGDQD GAYLFRTFLE REKCVDTLDF WFACNGFRQM 120
NLKDTKTLRV AKAIYKRYIE NNSIVSKQLK PATKTYIRDG IKKQQIDSIM FDQAQTEIQS 180
VMEENAYQMF LTSDIYLEYV RSGGENTAYM SNGGLGSLKV VCGYLPTLNE EEEWTCADFK 240
CKLSPTVVGL SSKTLRATAS VRSTETVDSG YRSFKRSDPV NPYHIGSGYV FAPATSANDS 300
EISSDALTDD SMSMTDSSVD GIPPYRVGSK KQLQREMHRS VKANGQVSLP HFPRTHRLPK 360
EMTPVEPATF AAELISRLEK LKLELESRHS LEERLQQIRE DEEKEGSELT LNSREGAPTQ 420
HPLSLLPSGS YEEDPQTILD DHLSRVLKTP GCQSPGVGRY SPRSRSPDHH HHHHSQYHSL 480
LPPGGKLPPA AASPGACPLL GGKGFVTKQT TKHVHHHYIH HHAVPKTKEE IEAEATQRVH 540
CFCPGGSEYY CYSKCKSHPK ALETMPSEQF GAQSTKKAYP LESARSSPGE RASRHHLWGG 600
NSGHPRTTPR AHLFTQDPAM PPLTPPNTLA QLEEACRRLA EVSKPPKQRC CVASQQRDRN 660
HSATVQTGAT PFSIPSLAPE DHKEPKKLAG VHALQASELV VTYFFCGEEI PYRRMLKAQS 720
LTLGHFKEQL SKKGNYRYYF KKASDEFACG AVFEEIWEDE TVLPMYEGRI LGKVERID 778

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologAXIN2490903E2R9F8Canis lupus familiarisPredictionMore>>
1:1 orthologAXIN2102180348A0A452FEH8Capra hircusPredictionMore>>
1:1 orthologAXIN28313Q9Y2T1Homo sapiensPublicationMore>>
1:1 orthologAxin212006O88566E13.5Mus musculusPredictionMore>>
1:1 orthologAXIN2468301A0A2I3SZU8Pan troglodytesPredictionMore>>
1:1 orthologAXIN2A0A287BFQ6Sus scrofaPredictionMore>>
1:1 orthologAxin2A0A0G2K4L4Rattus norvegicusPredictionMore>>
1:1 orthologaxin258080P57095Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016055 Wnt signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0879 Wnt signaling pathway

Interpro

InterPro ID InterPro Term
IPR014936 Axin_b-cat-bd
IPR032101 Axin_TNKS-bd
IPR001158 DIX
IPR038207 DIX_dom_sf
IPR016137 RGS
IPR036305 RGS_sf
IPR024066 RGS_subdom1/3
IPR029071 Ubiquitin-like_domsf

PROSITE

PROSITE ID PROSITE Term
PS50841 DIX
PS50132 RGS

Pfam

Pfam ID Pfam Term
PF16646 AXIN1_TNKS_BD
PF08833 Axin_b-cat_bind
PF00778 DIX
PF00615 RGS