| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3SC11 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000074384 |
| Ensembl nucleotide ID | ENSPTRG00000012571 |
| Gene name | Integrin beta |
| Gene symbol | ITGB6 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGIELLCLFF LFLGRNDHVQ GGCALGGAET CEDCLLIGPQ CAWCAQENFT HPSGVGERCD 60 TPANLLAKGC QLNFIENPVS QVEILKNKPL SVGRQKNSSD IVQIAPQSLI LKLRPGGAQT 120 LQVHVRQTED YPVDLYYLMD LSASMDDDLN TIKELGSRLS KEMSKLTSNF RLGFGSFVEK 180 PVSPFVKTTP EEIANPCSSI PYFCLPTFGF KHILPLTNDA ERFNEIVKNQ KISANIDTPE 240 GGFDAIMQAA VCKEKIGWRN DSLHLLVFVS DADSHFGMDS KLAGIVIPND GLCHLDSKNE 300 YSMSTVLEYP TIGQLIDKLV QNNVLLIFAV TQEQVHLYET GFRWVGRAGL QLLTASDPPA 360 LASRGAGIAD GVSLTQCSMV PRLECSGVIS ARYNLHLPAA CLGPPKCRDC SLCLAATLSG 420 RWGASLPGRP SSGMRGAPLP GCPMPLTPSN LQVFWGCEKH RAFCVTGNGD CDCGECVCRS 480 GWTGEYCNCT TSTDSCVSED GVLCSGRGDC VCGKCVCTNP GASGPTCERC PTCGDPCNSK 540 RSCIECHLSA AGQAREECVD KCKLAGATIS EEEDFSKDGS VSCSLQGENE CLITFLITTD 600 NEGKTIIHSI SEKDCPKPPN IPMIMLGVSL AILLIGVVLL CIWKLLVSFH DRKEVAKFEA 660 ERSKAKWQTG TNPLYRGSTS TFKNVTYKHR EKQKVDLSTD C 701 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGB6 | 282644 | Q8SQB8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ITGB6 | 102188539 | A0A452EJ04 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ITGB6 | 3694 | P18564 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itgb6 | 16420 | Q9Z0T9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ITGB6 | A0A2I3SC11 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A480ES98 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Itgb6 | 311061 | Q6AYF4 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | itgb6 | 100499533 | F1QGX0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009897 | external side of plasma membrane |
| GO:0005925 | focal adhesion |
| GO:0034685 | integrin alphav-beta6 complex |
| GO:0005178 | integrin binding |
| GO:0038023 | signaling receptor activity |
| GO:0033627 | cell adhesion mediated by integrin |
| GO:0016477 | cell migration |
| GO:0007160 | cell-matrix adhesion |
| GO:0006954 | inflammatory response |
| GO:0007229 | integrin-mediated signaling pathway |
| GO:0038044 | transforming growth factor-beta secretion |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00243 | INTEGRIN_BETA |