| Tag | Content |
|---|---|
| Uniprot ID | F1QGX0 |
| Entrez ID | 100499533 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_009305860.2; XM_003199426.4; XM_005155724.3; |
| Ensembl protein ID | ENSDARP00000065932; ENSDARP00000153217; |
| Ensembl nucleotide ID | ENSDARG00000002494 |
| Gene name | Integrin beta |
| Gene symbol | itgb6 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGIVSLCLVL YFWLDSVGGT CSQISALSCD DCLQLGPQCA WCTLQNFTDF FPVDERCDTP 60 EALLQKGCSG EFVEFPVTNV KVLKDQGLGK NSGHTNVSYI APQKMRLQLR PGSQLTFQIQ 120 VQQPKDHPVD IYYLMDLSAS MFDDLKKIKD LGSTLSKEMA NLTSKFRLGF GSFVEKPVLP 180 FIKITREELA NPCRSFDLEC LPTFGYRHLL SLTSSTDRFN EIISKQQISA NIDIPEGGFD 240 AIMQAAVCGD RIGWRNDSMK LLVFVSDADS HFGMDSKMSG IVVPNDGECH LDGNNEYSMT 300 AHLEYPTLGQ LVDKLVENNI LLIFAVTKDQ KENYENYASL IPGATVGVLA SDSRNILELI 360 MTSYKELRSE IDLEVLGNTE GLQMSFTALC QDGTITPGHK NCTNVKAGDV VSFNVTVEIK 420 GCLGGPRRFS LRPVGFQDAL EIELESQCVC SCHQTPETNS SFCSRGRGAL ECGECVCDPG 480 FVGPKCECTE SQDQVSDCRA NEGAEVCSGQ GECFCGQCVC LPSSFGRVYG PYCECDNFSC 540 LRFRGELCGG HGECDCGECV CDSGWMGEFC NCSTSNRSCV SSDGSVCSGR GRCVCGKCEC 600 SVPGASGKHC ERCPTCGDIC SIHRSCAECF LKAKEPSDEC AVKCSSLHTA VSNSTDFEES 660 RAAPCTLQSE ESCLLSFSLV ASDHGSIIYN PKLYDCSEPP NAPLIALGVC MSVLIIGIAL 720 LVIWKFLVSV HDRKEVAKFE AEKAKAKWQS GTNPLFRSST STFKNVTYKS TGQQKSDVSL 780 GR 782 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ITGB6 | 282644 | Q8SQB8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ITGB6 | 102188539 | A0A452EJ04 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ITGB6 | 3694 | P18564 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Itgb6 | 16420 | Q9Z0T9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ITGB6 | A0A2I3SC11 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | A0A480ES98 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Itgb6 | 311061 | Q6AYF4 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | itgb6 | 100499533 | F1QGX0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005925 | focal adhesion |
| GO:0034685 | integrin alphav-beta6 complex |
| GO:0005178 | integrin binding |
| GO:0038023 | signaling receptor activity |
| GO:0033627 | cell adhesion mediated by integrin |
| GO:0016477 | cell migration |
| GO:0007160 | cell-matrix adhesion |
| GO:0007229 | integrin-mediated signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR013111 | EGF_extracell |
| IPR040622 | I-EGF_1 |
| IPR033760 | Integrin_beta_N |
| IPR015812 | Integrin_bsu |
| IPR015436 | Integrin_bsu-6 |
| IPR014836 | Integrin_bsu_cyt_dom |
| IPR012896 | Integrin_bsu_tail |
| IPR036349 | Integrin_bsu_tail_dom_sf |
| IPR002369 | Integrin_bsu_VWA |
| IPR032695 | Integrin_dom_sf |
| IPR016201 | PSI |
| IPR036465 | vWFA_dom_sf |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00243 | INTEGRIN_BETA |