| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3SPH2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000078421 |
| Ensembl nucleotide ID | ENSPTRG00000007424 |
| Gene name | Aggrecan |
| Gene symbol | ACAN |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTTLLWVFVT LRVITAAVTV ETSDHDNSLS VSIPQPSPLR VLLGTSLTIP CYFIDPMHPV 60 TTAPSTAPLA PRIKWSRVSK EKEVVLLVAT EGRVRVNSAY QDKVSLPNYP AIPSDATLEV 120 QSLRSNDSGV YRCEVMHGIE DSEATLEVVV KGIVFHYRAI STRYTLDFDR AQRACLQNSA 180 IIATPEQLQA AYEDGFHQCD AGWLADQTVR YPIHTPREGC YGDKDEFPGV RTYGIRDTNE 240 TYDVYCFAEE MEGEVFYATS PEKFTFQEAA NECRRLGARL ATTGQLYLAW QAGMDMCSAG 300 WLADRSVRYP ISKARPNCGG NLLGVRTVYV HANQTGYPDP SSRYDAICYT GEDFVDIPEN 360 FFGVGGEEDI TIQTVTWPDM ELPLPRNITE GEARGSVILT VKPIFEVSPS PLEPEEPFTF 420 APEIGATAFP EVENETGEAT RPWGFPTPGL GPATAFTSED LVVQVTAVPG QPHLPGGVVF 480 HYRPGPTRYS LTFEEAQQAC LHTGAVIASP EQLQAAYEAG YEQCDAGWLR DQTVRYPIVS 540 PRTPCVGDKD SSPGVRTYGV RPSTETYDVY CFVDRLEGEV FFATRLEQFT FQEALEFCES 600 HNATLATTGQ LYAAWSRGLD KCYAGWLADG SLRYPIVTPR PACGGDKPGV RTVYLYPNQT 660 GLPDPLSRHH AFCFRGISAV PSPGEEEGGT PTSPSGVEEW IATQVVPGVA AVPVEEETTA 720 VPSGETTAIL EFTTEPENQT EWEPAYTPVG TSPLPGILPT WPPTGAATEE STEGPSATEV 780 PSASEEPSPS EVPFPSEEPS PSEEPFPSVR PFPSVELFPS EEPFPSKEPS PSEEPSASEE 840 PYTPSPPVPS WTELPSSGEE SGAPDVSGDF IGSGDVSGHL DFSGQLSGDR ASGLPSGDLD 900 SSGLTSTVGS VLPVESGLPS GDEERIEWPS TPTVGELPSG AEILEGSASG VGDLSGLPSG 960 EVLETSASGV GDLSGLPSGE VLETTAPGVE DISGLPSGEV LETTAPGVED ISGLPSGEVL 1020 ETTAPGVEDI SGLPSGEVLE TTLPWKVLET TAPGVEDISG LPSGEVLETT APGVEDQCAS 1080 FWKVLETTAP GVEDISGIED ISGLPSGEVL ETTAPESRGH QRISGLPSGE VLETTAPGVE 1140 DISGLPSGEV LETTAPGVED ISGLPSGEVL ETTAPGVEDI SGLPSGEVLE TTASGVEDIS 1200 GLPSGEVLET TAPGVEEISG LPSGEVLETT ASGVEEISGL PSGEVLETST SAVGDVSGPP 1260 SGGEVLEISA SGVEDISGLP SGEVVETSAS GIEDVSELPS GEGLETSASG VEDLSRLPSG 1320 EEVLEISASG FGDLSGLPSG GEGLETSASE VGTDLSGLPS GREGLETSAS GAEDLSGLPS 1380 GKEDLVGSAS GDLDLGKLPS GTLGSGQAPE TSGLPSGFSG EYSGVDLGSG PPSGLPDFSG 1440 LPSGFPTVSL VDSTLVEVVT ASTASELEGR GTIGISGAGE ISGLPSSELD ISGRASGLPS 1500 GTELSGQASG SPDVSGEIPG LFGVSGQPSG FPDTSGETSG VTELSGLSSG QPGVSGEASG 1560 VLYGTSQPFG ITDLSGETSG VPDLSGQPSG LPGFSGATSG VPDLVSGTTS GSGESSGITF 1620 VDTSLVEVAP TTFKEEEGLG SVELSGLPSG EADLSGKSGM VDVSGQFSGT VNSSGFTSQT 1680 PEFSGLPSGI AEVSGESSRA EIGSSLPSGA YYGSGTPSSF PTVSLVDRTL VESVTQAPTA 1740 QEAGEGPSGI LELSGAHSGA PDMSGEHSGF LDLSGLQSGL VEPSGEPPGT PYFSGDFAST 1800 TNVSRESSVA MGTSGEASGL PEVTLITSEF VEGVTEPTVS QELGQRPPVT HTPQLFESSG 1860 DVSTAGDVSG ATPVLPGSGV EVSSVPESSS ETSAYPEAGF GASAAPEASR EDSGSPDLSE 1920 TTSAFHEADL ERSSGLGVSG STLTFQEGEA SAAPEVSGES TTTNDVGTEA PGLPSATPTA 1980 SGDRTEISGD PSGHTLRLGV VISTSIPESE WTQQTQRPAE THLEIESSSL LYSGEETHTV 2040 KTATSPTDAS IPASPEWKRE SESTAADQEV CEEGWNKYQG HCYRHFPDRE TWVDAERRCR 2100 EQQSHLSSIV TPEEQEFVNN NAQDYQWIGL NDRTIEGDFR WSDGHPMQFE NWRPNQPDNF 2160 FAAGEDCVVM IWHEKGEWND VPCNYHLPFT CKKGTATTYK RRLQKRSSRH PRRSRPSTAH 2220 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ACAN | F1N368 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | ACAN | 403828 | A0A5F4DFW2 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ACAN | A0A452FGP3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ACAN | 176 | P16112 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Acan | 11595 | Q61282 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ACAN | A0A2I3SPH2 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ACAN | A0A287BRK5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | ACAN | 100009079 | G1U677 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Acan | D4A7Y1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030246 | carbohydrate binding |
| GO:0005540 | hyaluronic acid binding |
| GO:0007155 | cell adhesion |