| Tag | Content |
|---|---|
| Uniprot ID | A0A3Q2HPQ1 |
| Entrez ID | 100065774 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001504686.3 |
| Ensembl protein ID | ENSECAP00000036995 |
| Ensembl nucleotide ID | ENSECAG00000020022 |
| Gene name | Insulin-induced gene protein |
| Gene symbol | INSIG1 |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Mediates feedback control of cholesterol synthesis. |
| Sequence | MPRLDDHFWS CSCAKGRRHR SHQRTGSGGV AAKVGKMINS SVPGPSLLVA HSAPDTDPSR 60 GPQSTGVGGR GASSCHTNSW HHHLVQRSLV LFSVGVVLAL VLNLLQVQRN VTLFPEEVIA 120 TIFSSAWWVP PCCGTAAAVV GLLYPCIDSH LGEPHKFKRE WASVMRCVAV FVGINHASAK 180 LDFANNVQLS LTLAALSLGL WWTFDRSRSG LGLGITIAFL ATLITQLLVY NGVYQYTSPD 240 FLYIRSWLPC IFFSGGVTVG NIGRQLAMGV PEKPHSD 277 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | INSIG1 | 511899 | A0JNC3 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | INSIG1 | 475554 | A0A5F4D7Y9 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | INSIG1 | A0A452FSS4 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | INSIG1 | 100065774 | A0A3Q2HPQ1 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | INSIG1 | 3638 | O15503 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Insig1 | 231070 | Q8BGI3 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | INSIG1 | 463839 | H2QVN6 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | insig1 | 334189 | Q8AV61 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0008203 | cholesterol metabolic process |
| Pfam ID | Pfam Term |
|---|---|
| PF07281 | INSIG |