CleftGeneDB-Search

Gene: SPRY2

Basic information

Tag	Content
Uniprot ID	A0A452DWT1
Entrez ID	102188779
Genbank protein ID
Genbank nucleotide ID	XM_018056458.1
Ensembl protein ID	ENSCHIP00000004142
Ensembl nucleotide ID	ENSCHIG00000008359
Gene name	Uncharacterized protein
Gene symbol	SPRY2
Organism	Capra hircus
NCBI taxa ID	9925
Cleft type
Developmental stage
Data sources	Homology search
Reference
Functional description
Sequence	MEARAQSGSG SQPLLQTPRD SGRQRGEPDP RDALPQQVHV LSLDQIRAIR NTNEYTEGPT 60 VLPRAGLKPA PRPTTQHKHE RLHGLPEPRQ PARPQHPPAH PSARAPLARS ISTVSSGSRS 120 STRTSTSSSS SEQRLLGSSF SSGPLADRII RVQPKSELKP GELKPLSKED VGLHAYKCED 180 CGKCKCKECT YPRPLPSDWI CDKQCLCSAQ NVIDYGTCVC CVKGLFYHCS NDDEDNCADN 240 PCSCSQSHCC TRWSAMGVMS LFLPCLWCYL PAKGCLKLCQ GCYDRVNRPG CRCKNSNTVC 300 CKVPTVPPRN FEKPT 315

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

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Relation	Gene symbol	Entrez ID	UniProt ID	Cleft type	Developmental stage	Species	Evidence	Details
1:1 ortholog	Spry2	24064	Q9QXV8	CPO	E13.5, E14.5, E16.5	Mus musculus	Publication	More>>
1:1 ortholog	SPRY2	539090	Q08E39			Bos taurus	Prediction	More>>
1:1 ortholog	SPRY2	485504	E2RGU9			Canis lupus familiaris	Prediction	More>>
1:1 ortholog	SPRY2	102188779	A0A452DWT1			Capra hircus	Prediction	More>>
1:1 ortholog	SPRY2		F6UL06			Equus caballus	Prediction	More>>
1:1 ortholog	SPRY2	10253	O43597			Homo sapiens	Prediction	More>>
1:1 ortholog	SPRY2		H2Q7P2			Pan troglodytes	Prediction	More>>
1:1 ortholog	SPRY2	100157266	F1RP67			Sus scrofa	Prediction	More>>
1:1 ortholog	SPRY2	100352158	G1SXJ1			Oryctolagus cuniculus	Prediction	More>>
1:1 ortholog	Spry2	306141	Q5HZA2			Rattus norvegicus	Prediction	More>>

Showing 1 to 10 of 11 entries

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Gene ontology

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GO ID	GO Term
GO:0000132	establishment of mitotic spindle orientation
GO:0005623	cell
GO:0005634	nucleus
GO:0005829	cytosol
GO:0007605	sensory perception of sound
GO:0008285	negative regulation of cell population proliferation
GO:0010628	positive regulation of gene expression
GO:0010801	negative regulation of peptidyl-threonine phosphorylation
GO:0015629	actin cytoskeleton
GO:0016020	membrane
GO:0016525	negative regulation of angiogenesis
GO:0019901	protein kinase binding
GO:0030335	positive regulation of cell migration
GO:0031345	negative regulation of cell projection organization
GO:0033138	positive regulation of peptidyl-serine phosphorylation
GO:0034260	negative regulation of GTPase activity
GO:0035924	cellular response to vascular endothelial growth factor stimulus
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
GO:0042472	inner ear morphogenesis
GO:0043066	negative regulation of apoptotic process