| Tag | Content |
|---|---|
| Uniprot ID | A0A452E119 |
| Entrez ID | 102169794 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018063805.1 |
| Ensembl protein ID | ENSCHIP00000005703 |
| Ensembl nucleotide ID | ENSCHIG00000009742 |
| Gene name | ATP-dependent DNA helicase |
| Gene symbol | RECQL5 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSSHPSSPFD PERRVRSMLK KVFGFDSFKT PLQERAIMAV VKGDKDVFVC MPTGAGKSLC 60 YQLPALLAKG ITIVVSPLIA LIQDQVDHLL ALKVRVSSLN SKLSVQERKE LLSDLEQEKP 120 QTKLLYITPE MAASTSFQPT LNSLVSRQLL SYLVVDEAHC VSQWGHDFRP DYLRLGALRS 180 RLADAPCVAL TATATPQVRE DVFAALHLKQ PVAIFKTPCF RANLFYDVQF KELLPDPYGN 240 LRDFCLKALG QKADKGLSGG GIIYCRTREA CEQLAIELSY RGVNAKAYHA GLKAPERTLV 300 QNEWMEEKVP VIVATISFGM GVDKANVRFV AHWNIAKSMA GYYQESGRAG RDGKPSWCRL 360 YYSRSDRDQV SFLIRKEVAK LQEKRGNKAS DKAAVLAFDA LVAFCEESGC RHAAIAKYFG 420 DLPPACTKGC DCCQNPAGVR KQLDALEQRS SWNKTCIGPS QGNGYDPELY EGGRRGYGGF 480 SRYDEGSGGS GDEGRDEAQK REWNLFYQKQ MRLRKGKDPK TEEFIPPDED CPLREAASRK 540 IPRLTVKARE HCLGLLEEAL SSNHQAAGSA DGLDLQAKAV ELEHETFRSA KVANLYKASV 600 LKKVAEIHRA SKEGQLYCVG GSTSSCSAQA EPPEPTEHDI LPASQVYSLK PKRVGAGFPK 660 GSCLFQTATE LMEKTWVPEQ EPRPEQGGEQ GGEQGAPSQP CDRQGTECAE PLPGLRGEAP 720 RSDAVCRGPS PEEERGPARG SPTAKVRVNK KQQLLAAAAL KDSQNITRFF CRRTKSPPPL 780 TAALGADSAS PSRDGVWRSL TLLEKGSGQE DGAVGRLAAR PDTKECAEEG PSACPLRDQR 840 PPEGQPSPTE EAQRGKRPRP QQENAGSQAQ KRPRPSAKAS ILAEAKGSVS ASDQRPPSPQ 900 GSCQLSAPSI SLKEAASVVV KCLTPFYKEG KFASKELFKA FARHLSHSLT QNLCPGRSVK 960 EEAQDVIKQL FRGRARCESE ADWHGLCGLQ R 991 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | RECQL5 | 512590 | E1BKM5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 483317 | F1PAG8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 102169794 | A0A452E119 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 9400 | O94762 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Recql5 | 170472 | Q8VID5 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | G1TZG6 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Recql5 | 287834 | D4ACP5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | recql5 | 566553 | X1WCM8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0016591 | RNA polymerase II, holoenzyme |
| GO:0005524 | ATP binding |
| GO:0003678 | DNA helicase activity |
| GO:0003676 | nucleic acid binding |
| GO:0000993 | RNA polymerase II complex binding |
| GO:0072757 | cellular response to camptothecin |
| GO:0051304 | chromosome separation |
| GO:0006260 | DNA replication |
| GO:0000278 | mitotic cell cycle |
| GO:2000042 | negative regulation of double-strand break repair via homologous recombination |
| GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter |
| GO:1990414 | replication-born double-strand break repair via sister chromatid exchange |