| Tag | Content |
|---|---|
| Uniprot ID | F1PAG8 |
| Entrez ID | 483317 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_540436.5 |
| Ensembl protein ID | ENSCAFP00000007269 |
| Ensembl nucleotide ID | ENSCAFG00000004860 |
| Gene name | ATP-dependent DNA helicase |
| Gene symbol | RECQL5 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSAHPFDRER RVRSTLKKVF GFDSFKTPLQ ESATMAVVRG DKDVFVCMPT GAGKSLCYQL 60 PALLAKGITI VVSPLIALIQ DQVDHLLALK VRVSSLNSKL SAQEKKELLS DLEREKPQTK 120 LLYITPEMAA SPSFQPTLNS LVSRHLLSYL VVDEAHCVSQ WGHDFRPDYL RLGTLRSRLA 180 HAPCIALTAT ATLQVQEDVF AALHLKQPVA TFKTPCFRAN LFYDVQFKEL LSDPYGNLRD 240 FCLKALGQKA DKGLLSGCGI VYCRTREACE QLATELSYRG VNAKAYHAGL KASERTLVQN 300 EWMEEKVPVI VATISFGMGV DKANVRFVAH WNIAKSMAGY YQESGRAGRD GKPSWCRLYY 360 SRNDRDQVSF LIRKEVAKLQ EKRGNKASDK AAILAFDALV TFCEELGCRH AAIAKYFGDA 420 PPACTKGCDH CRDPAALRKR LDALEHSSSW NKTCIGPSQG NGFDPELYEG GRRGYGGFSR 480 YDEGSGGSGD EGRDEAHKRE WNLFYQKQMS LRKGKDPKIE EFVPPDEDCP LKEASSRKIP 540 RLTVKAREHC LGLLEEALSS NCQATSTTHG PDLQAKAVEL EHEMFRNAKM ANLYKASVLK 600 KVAEIHRASK DGQLYDVGSN TRSCSMHAQP PEPTEYDIRP ASQVYSLKPK RVGAGFPRGS 660 CPFQTATELM EKTQAEERAP QPVQEGKREP PSQPCGLQDE DCSKALPGPR AEAPGSSFHC 720 GGSSPEKTGK SPSKGGPLAK ARASKKQQLL AAAALKDSQN ITRFCLRAKS PSPLTSAPGA 780 EDAGPGPSCE GMRGPPAAPE KCAGEEDGAL GCLAAHPQTK ECTRERPRAY TLGDQGSPEG 840 QPIPTEETPR GKRPRPQQEN LEKQTQKRPR PSANASVLAE AKDGIPAWNQ DTLNPTAQGS 900 CLLPAPGISL KEAANVVVKC LTPFYKEGKF ASKELFKAFA RHLSHSLTQK ASPGRSVKEE 960 AQTFIKQFFH GRARCESEAD WHGLCDPQR 989 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | RECQL5 | 512590 | E1BKM5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 483317 | F1PAG8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 102169794 | A0A452E119 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 9400 | O94762 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Recql5 | 170472 | Q8VID5 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | G1TZG6 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Recql5 | 287834 | D4ACP5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | recql5 | 566553 | X1WCM8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005694 | chromosome |
| GO:0005737 | cytoplasm |
| GO:0005829 | cytosol |
| GO:0005634 | nucleus |
| GO:0016591 | RNA polymerase II, holoenzyme |
| GO:0043138 | 3'-5' DNA helicase activity |
| GO:0005524 | ATP binding |
| GO:0009378 | four-way junction helicase activity |
| GO:0003676 | nucleic acid binding |
| GO:0000993 | RNA polymerase II complex binding |
| GO:0072757 | cellular response to camptothecin |
| GO:0051304 | chromosome separation |
| GO:0032508 | DNA duplex unwinding |
| GO:0006310 | DNA recombination |
| GO:0006281 | DNA repair |
| GO:0006268 | DNA unwinding involved in DNA replication |
| GO:0000724 | double-strand break repair via homologous recombination |
| GO:0000278 | mitotic cell cycle |
| GO:2000042 | negative regulation of double-strand break repair via homologous recombination |
| GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter |
| GO:1990414 | replication-born double-strand break repair via sister chromatid exchange |