| Tag | Content |
|---|---|
| Uniprot ID | X1WCM8 |
| Entrez ID | 566553 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005164274.3 |
| Ensembl protein ID | ENSDARP00000127973 |
| Ensembl nucleotide ID | ENSDARG00000059556 |
| Gene name | ATP-dependent DNA helicase |
| Gene symbol | recql5 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSVVHRALKT HFGFEKFRSR QQEEAVNALL QGDRDVFVCM PTGAGKSLCY QLPALMASGV 60 TLVISPLIAL IQDQVEHLKA LNVPARSINS KLPLAERRQI LADLESETPR LKLLYITPEM 120 VASPSFQPVL SSLSSRGLLG YLAVDEAHCV SQWGHDFRPD YLKLGDLRSR LQGIRCIALT 180 ATAPKRVKED IERSLRLRSP LVFSTPVFRK NLKYDVIFRD LLPEPYVHLL AFAKEALGGN 240 TAEKGCGIVY CRTRESCEEV AHKLTKLGIA AKPYHAGLKS GDRSENQADW MADKVPIIVA 300 TISFGMGVDK ANVRFVVHWN LAKSLASYYQ ESGRAGRDGL PSSCRIYYSP KDRDQLNFLI 360 RKEISRKQEK RGSEKEQDKA PILDFEAMVA FCEQEGCRHA TISTFFGNEK PNCAGACDFC 420 RDPKLVRAQL ARAAALSTRT NPTHSAEPRG PFGFDPELYA GGRKGYGFER HDEEYGSEED 480 DSEKRKKQFG DLFKKQMSLR KGSDAPKETF VPPDADCVLK DASSQRIPRL TVKSREHCLS 540 LLQECLSSHS GDAEFLHRSE ALDQAVDIEH EIFKSSKSAN IYKAAVLKRV SEMKKSTSVS 600 VTEEKPCESA EEKPTCSSSA QHLDGFTSAS QIYSLKRKRV GAGFRGSSSL FQPAGDLLKS 660 SDQTPGDSTC EEESGKTQKD NNNTSSIKAK SGSSSSLNSP SKKLSRKQQK LAEAARDTRL 720 ISLYFGKKQA QRESSPEPEE TEDACEDRSA SANGVHTLSS SSVDAERAAQ ESLCEVTAHA 780 EDYGENQQSD GQRKSPKQAH EDRSEVRAPS PPVKRRRVLK DTKRVTFDPV VQETQVEALN 840 GDGAGISRKP VTLKEAADIV VRCLDPFYKQ GKFATKDLFK SFARFLSHLL TEGKTPNRGQ 900 VKLEAKRLIK RFFSRTVRCE SESDWMLLKT QDR 933 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | RECQL5 | 512590 | E1BKM5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 483317 | F1PAG8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 102169794 | A0A452E119 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 9400 | O94762 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Recql5 | 170472 | Q8VID5 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | G1TZG6 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Recql5 | 287834 | D4ACP5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | recql5 | 566553 | X1WCM8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005694 | chromosome |
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0043138 | 3'-5' DNA helicase activity |
| GO:0005524 | ATP binding |
| GO:0009378 | four-way junction helicase activity |
| GO:0003676 | nucleic acid binding |
| GO:0032508 | DNA duplex unwinding |
| GO:0006310 | DNA recombination |
| GO:0006281 | DNA repair |
| GO:0006268 | DNA unwinding involved in DNA replication |
| GO:0000724 | double-strand break repair via homologous recombination |
| GO:0045950 | negative regulation of mitotic recombination |