| Tag | Content |
|---|---|
| Uniprot ID | E1BKM5 |
| Entrez ID | 512590 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001192326.1; XM_005221208.3; |
| Ensembl protein ID | ENSBTAP00000015555 |
| Ensembl nucleotide ID | ENSBTAG00000011715 |
| Gene name | ATP-dependent DNA helicase |
| Gene symbol | RECQL5 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSTHPSSPFD PERRVRSTLK KVFGFDSFKT PLQEKAIMAV VKGDKDVFVC MPTGAGKSLC 60 YQLPALLAKG ITIVVSPLIA LIQDQVDHLL ALKVRVSSLN SKLSVQERKE LLSDLEQEKP 120 QTKLLYITPE MAASTSFQPT LNSLVSRHLL SYLVVDEAHC VSQWGHDFRP DYLRLGALRS 180 RLADAPCVAL TATATPQVRE DVFAALHLKQ PVATFKTPCF RANLFYDVQF KELLPDPYGN 240 LRDFCLKALG QKADKGLSGC GIIYCRTREA CEQLATELSY RGVNAKAYHA GLKAPERTLV 300 QNEWMEEKVP VIVATISFGM GVDKANVRFV AHWNIAKSMA GYYQESGRAG RDGKPSWCRL 360 YYSRSDRDQV SFLIRKEVAK LQEKRGNKAS DKAAVLAFDA LVAFCEESGC RHAAIAKYFG 420 DSPPACTKGC DCCQNPTGVR KQLDALEQRS SWNKTCIGPS QGNGYDPELY EGGRRGYGGF 480 SRYDEGSGGS GDEGRDEAQK REWNLFYQKQ MRLRKGKDPK TEEFVPPDED CPLREAASRK 540 IPRLTVKARE HCLGLLEEAL SSNRQAAGST DGLDLQAKAV ELEHETFRNA KVANLYKASV 600 LKKVAEIHRA SKDGQLYRVG GGASSCSAQA EPPEPTEHDI LPASQVYSLK PKRVGAGFPK 660 GSCLFQTATE LMEKTWVPEQ EPRPKQGGER GAPSQPCDCQ GAEPAKSLPG PQGEAPRSGA 720 VCRGPSPEEE RGPARGSPTA KARVNKKQQL LAAAALKDSQ NIARFFCRRT KSPPPVTAAP 780 GADGTSPSRD GARGPLTFLE KGSGQEDGAV GHLAARPETK ECAEEGPSAC PLRDQRPPEG 840 QPSPTEEAQR GKRPRPQQES PGSQAQKRPR PSAKASILAE AKGSVSASDQ RPSIPQGSCQ 900 LLAPSISLKE AANVVVKCLT PFYKEGKFAS KELFKAFARH LSHSLTQNPC PGRSVKEEAQ 960 DVIKQLFHGR ARCESEADWH GLCGPQR 987 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | RECQL5 | 512590 | E1BKM5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 483317 | F1PAG8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 102169794 | A0A452E119 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 9400 | O94762 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Recql5 | 170472 | Q8VID5 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | G1TZG6 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Recql5 | 287834 | D4ACP5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | recql5 | 566553 | X1WCM8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005694 | chromosome |
| GO:0005737 | cytoplasm |
| GO:0005829 | cytosol |
| GO:0005634 | nucleus |
| GO:0016591 | RNA polymerase II, holoenzyme |
| GO:0043138 | 3'-5' DNA helicase activity |
| GO:0005524 | ATP binding |
| GO:0009378 | four-way junction helicase activity |
| GO:0003676 | nucleic acid binding |
| GO:0000993 | RNA polymerase II complex binding |
| GO:0072757 | cellular response to camptothecin |
| GO:0051304 | chromosome separation |
| GO:0032508 | DNA duplex unwinding |
| GO:0006310 | DNA recombination |
| GO:0006281 | DNA repair |
| GO:0006268 | DNA unwinding involved in DNA replication |
| GO:0000724 | double-strand break repair via homologous recombination |
| GO:0000278 | mitotic cell cycle |
| GO:2000042 | negative regulation of double-strand break repair via homologous recombination |
| GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter |
| GO:1990414 | replication-born double-strand break repair via sister chromatid exchange |