| Tag | Content |
|---|---|
| Uniprot ID | G1TZG6 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSOCUP00000022488 |
| Ensembl nucleotide ID | ENSOCUG00000016202 |
| Gene name | ATP-dependent DNA helicase |
| Gene symbol | RECQL5 |
| Organism | Oryctolagus cuniculus |
| NCBI taxa ID | 9986 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSARPPPNPS DPERRVRSTL KKVFGFDSFK TPLQERATMA VVKGDKDVFV CMPTGAGKSL 60 CYQLPALLAT GITIVISPLI ALIQDQVDHL SALKVPVSSL NSKLSAQERK ELLSDLEREK 120 PQTRLLYITP EMAASASFQP TLHSLVSRCL LSYLVVDEAH CVSQWGHDFR PDYLRLGALR 180 ARLAHTPCVA LTATATPQVQ EDVFAALHLK PPVATFKTPC FRANLFYDVQ FKELISDPFG 240 NLRDFCLKAL GQKTNKGVLS GCGIVYCRTR EACEQLAMEL SCRGVSAKAY HAGLKASDRT 300 LVQNEWMEEK VPVIVATISF GMGVDKANVR FVAHWNIAKS MAGYYQESGR AGRDGKPSWC 360 RLYYSRSDRD QVNFLIRKEI AKLQEKRGNK ASDKATLCAF DALVTFCEEQ GCRHAAIAKY 420 FGDAPPACSK GCDHCQNPAA VRRQLDALER SSSWSKTCIG PSKGDGFDPE LYEGGRRGYG 480 GFSRYDEGSG GSGDEAKDEA HKREWNLFYQ KQMNLRKGKD PKTEEFVPPD EDCPLEEASS 540 RKIPRLTVKA REHCLGLLEE ALSSNRQATG TSDGASLLAK AVELEHEMFR NAKMANLYKA 600 SVLKKVAEIH KASKDGQLYD TGGGAKKRSA QAEPSEPSEY DIPPASQVYS LKAKRVGAGF 660 PKGSCLFQTA TELMGKTQPQ DGAPQPVQRE EQEPPSQPCA LQDEGCSEPL PGPRPKASGG 720 GAHCGGPSPE KKAKGSPGSQ SVAKTSASKK QQLLAAAARK DSQDITRFFC QRAGSPAPGA 780 EDASPACGGV QETPPEKCAE EEDGARAQGR LPAPLQTEEC PGAGPGSQGP PASHPGPPEE 840 TQRGKRPRPQ QDDPESQAQK RPCPSAKRSV SAEAKGSIPA SDQDSRNPTA QGPSQLSAPG 900 IPLKESCEHC GQVSDTFLQG GQVCIQGAVQ RLRPPPVPPP DSEALSRKER ERRGPEPHQA 960 VLPRPDPVRE |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | RECQL5 | 512590 | E1BKM5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 483317 | F1PAG8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 102169794 | A0A452E119 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | 9400 | O94762 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Recql5 | 170472 | Q8VID5 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | RECQL5 | G1TZG6 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Recql5 | 287834 | D4ACP5 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | recql5 | 566553 | X1WCM8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0016591 | RNA polymerase II, holoenzyme |
| GO:0005524 | ATP binding |
| GO:0003678 | DNA helicase activity |
| GO:0003676 | nucleic acid binding |
| GO:0000993 | RNA polymerase II complex binding |
| GO:0072757 | cellular response to camptothecin |
| GO:0051304 | chromosome separation |
| GO:0006260 | DNA replication |
| GO:0000278 | mitotic cell cycle |
| GO:2000042 | negative regulation of double-strand break repair via homologous recombination |
| GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter |
| GO:1990414 | replication-born double-strand break repair via sister chromatid exchange |