| Tag | Content |
|---|---|
| Uniprot ID | A0A452E880 |
| Entrez ID | 102186699 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005687682.3 |
| Ensembl protein ID | ENSCHIP00000008345 |
| Ensembl nucleotide ID | ENSCHIG00000011534 |
| Gene name | G_PROTEIN_RECEP_F1_2 domain-containing protein |
| Gene symbol | EDNRB |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MQPLPSLCGR ALVALILACG VAGIQAEERE FPPAGATQPL LGTGEMMETP TETSWPGRSN 60 ASEPRSSATP QVPRGGRMVG IPPRTPPPCD GPIEIKETFK YINTVVSCLV FVLGIIGNST 120 LLRIIYKNKC MRNGPNILIA SLALGDLLHI IIDIPINTYK LLAKDWPFGV EMCKLVPFIQ 180 KASVGITVLS LCALSIDRYR AVASWSRIKG IGVPKWTAVE IVLIWVVSVV LAVPEAVGFD 240 IITSDHIGNN LRICLLHPTQ KTAFMQFYKT AKDWWLFSFY FCLPLAITAL FYTLMTCEML 300 RKKSGMQIAL NDHLKQRREV AKTVFCLVLV FALCWLPLHL SRILKLTLYD QHDPRRCEFL 360 SFLLVLDYIG INMASLNSCI NPIALYLVSK RFKNCFKSCL CCWCQSFEEK QSLEEKQSCL 420 KFKANDHGYD NFRSSNKYSS S 441 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EDNRB | 281750 | P28088 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 403862 | F1PB15 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 102186699 | A0A452E880 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 1910 | P24530 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ednrb | 13618 | P48302 | CPO,CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | EDNRB | 452613 | H2Q7N9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 414911 | P35463 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 100009477 | D6CI21 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Ednrb | 50672 | P21451 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ednrba | 30442 | Q9DGM2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0004962 | endothelin receptor activity |
| GO:0017046 | peptide hormone binding |
| GO:0019722 | calcium-mediated signaling |
| GO:0048484 | enteric nervous system development |
| GO:0035645 | enteric smooth muscle cell differentiation |
| GO:0048246 | macrophage chemotaxis |
| GO:0030318 | melanocyte differentiation |
| GO:0032269 | negative regulation of cellular protein metabolic process |
| GO:0014043 | negative regulation of neuron maturation |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0001755 | neural crest cell migration |
| GO:0007422 | peripheral nervous system development |
| GO:0007497 | posterior midgut development |
| GO:0008217 | regulation of blood pressure |
| GO:0006885 | regulation of pH |
| GO:0014826 | vein smooth muscle contraction |
| Pfam ID | Pfam Term |
|---|---|
| PF00001 | 7tm_1 |