| Tag | Content |
|---|---|
| Uniprot ID | F1PB15 |
| Entrez ID | 403862 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005633820.2 |
| Ensembl protein ID | ENSCAFP00000007760 |
| Ensembl nucleotide ID | ENSCAFG00000005187 |
| Gene name | Endothelin receptor type B |
| Gene symbol | EDNRB |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MKPLLSWCRR ALVALILACS GAGVQGEERG FPPARATVPL WGPGEITTPP TEASWSKGPN 60 ASVPWSSAPP QMPKGGRTAG GPPRTLTPPP CEKSIEIKET FKYINTVVSC LVFVLGIIGN 120 STLLRIIYKN KCMRNGPNIL IASLALGDLL HIIIDIPITV YKLLAEDWPF GVEMCKLVPF 180 IQKASVGITV LSLCALSIDR YRAVASWSRI KGIGVPKWTA VEIVLIWVVS VVLAVPEAVG 240 FDMITIDYKG RYLRICLLHP TQKTAFMQFY KTAKDWWLFS FYFCLPLAIT AFFYTLMTCE 300 MLRKKSGMQI ALNDHLKQRR EVAKTVFCLV LVFALCWLPL HLSRILKLTI YDQNDPNRCE 360 LLSFLLVLDY IGINMASLNS CINPIALYLV SKRFKNCFKS CLCCWCQSFE EKQSLEEKQS 420 CLKFKANDHG YDNFRSSNKY SSS 443 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EDNRB | 281750 | P28088 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 403862 | F1PB15 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 102186699 | A0A452E880 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 1910 | P24530 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ednrb | 13618 | P48302 | CPO,CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | EDNRB | 452613 | H2Q7N9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 414911 | P35463 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | EDNRB | 100009477 | D6CI21 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Ednrb | 50672 | P21451 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ednrba | 30442 | Q9DGM2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0004962 | endothelin receptor activity |
| GO:0017046 | peptide hormone binding |
| GO:0019722 | calcium-mediated signaling |
| GO:0048484 | enteric nervous system development |
| GO:0035645 | enteric smooth muscle cell differentiation |
| GO:0048246 | macrophage chemotaxis |
| GO:0030318 | melanocyte differentiation |
| GO:0032269 | negative regulation of cellular protein metabolic process |
| GO:0014043 | negative regulation of neuron maturation |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0001755 | neural crest cell migration |
| GO:0007422 | peripheral nervous system development |
| GO:0007497 | posterior midgut development |
| GO:0008217 | regulation of blood pressure |
| GO:0006885 | regulation of pH |
| GO:0014826 | vein smooth muscle contraction |
| Pfam ID | Pfam Term |
|---|---|
| PF00001 | 7tm_1 |