Gene: ednrba

Basic information

Tag Content
Uniprot ID Q9DGM2
Entrez ID 30442
Genbank protein ID AAG00977.1; CAE17596.1;
Genbank nucleotide ID NM_131197.1
Ensembl protein ID ENSDARP00000111210
Ensembl nucleotide ID ENSDARG00000089334
Gene name Endothelin receptor non-selective type
Gene symbol ednrba
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MRFQIIMETR CVFCFLFLLT EHIAVMSAQG KDFNQSRLSM GPLSPTQKST IVIGNQINES 60
MPRRPKVLPP MCTDPTEIRD TFKYINTVVS CLVFVVGIIG NSTLLRIIYK NKCMRNGPNI 120
LIASLALGDL LHIMIDIPIN VYKLLAKDWP FGVGLCKLVP FIQKTSVGIT ILSLCALSID 180
RFRAVSSWNR IKGIGVPKWT AIEIILIWVL SIILAVPEAI AFDMITMDYK GEQLRICLLH 240
PKQRIKFMQF YKKAKDWWLF SFYFCMPLTC TAIFYTLMTC EMLRKKNGVQ IALSDHIKQR 300
REVAKTVFCL VLVFALCWLP LHLSRILQRT IYDERDPNRC ELLSFFLVLD YIGINMASVN 360
SCINPIALYM VSKRFKSCFR SCLCCWCLPP EILAMDDKQS CIKLKVTERG SAITAMSPTS 420
ILQIRH 426

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologEDNRB281750P28088Bos taurusPredictionMore>>
1:1 orthologEDNRB403862F1PB15Canis lupus familiarisPredictionMore>>
1:1 orthologEDNRB102186699A0A452E880Capra hircusPredictionMore>>
1:1 orthologEDNRB1910P24530Homo sapiensPredictionMore>>
1:1 orthologEdnrb13618P48302CPO,CLPMus musculusPublicationMore>>
1:1 orthologEDNRB452613H2Q7N9Pan troglodytesPredictionMore>>
1:1 orthologEDNRB414911P35463Sus scrofaPredictionMore>>
1:1 orthologEDNRB100009477D6CI21Oryctolagus cuniculusPredictionMore>>
1:1 orthologEdnrb50672P21451Rattus norvegicusPredictionMore>>
1:1 orthologednrba30442Q9DGM2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0005886 plasma membrane
GO:0004962 endothelin receptor activity
GO:0048066 developmental pigmentation
GO:0048484 enteric nervous system development
GO:0050935 iridophore differentiation
GO:0008217 regulation of blood pressure
GO:0048070 regulation of developmental pigmentation
GO:0042310 vasoconstriction

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0297 G-protein coupled receptor
KW-0472 Membrane
KW-0675 Receptor
KW-1185 Reference proteome
KW-0732 Signal
KW-0807 Transducer
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR000499 Endthln_rcpt
IPR001112 ETB_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM

PROSITE

PROSITE ID PROSITE Term
PS00237 G_PROTEIN_RECEP_F1_1
PS50262 G_PROTEIN_RECEP_F1_2

Pfam

Pfam ID Pfam Term
PF00001 7tm_1