| Tag | Content |
|---|---|
| Uniprot ID | A0A452EMB1 |
| Entrez ID | 102173426 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018066938.1 |
| Ensembl protein ID | ENSCHIP00000012957 |
| Ensembl nucleotide ID | ENSCHIG00000014531 |
| Gene name | Uncharacterized protein |
| Gene symbol | TWF2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAHQTGIHAT EELKEFFAKA RAGSVRLIKV VIEDEQLVLG AFRELVGCWD QDYDGAVLPL 60 LDAQQPCYLL YRLDSQNAQG FEWLFLAWSP DNSPVRLKML YAATRATVKK EFGGGHIKDE 120 LFGTVKDDLS FAGYQKHLSS CAAPAPLTSA ERELQQIRIN EVKTEISVES KHQTLQGLAF 180 PLQPQAQRAL QQLRQKAINY IQLKLDLERE TIELVHTEPT DVAQLPSRVP RDAARYHFFL 240 YKHTHEGDPL ESVVFIYSMP GYKCSIKERM LYSSCKSRLL DSVEQDFQLE VAKKIEIGDG 300 AELTADFLYD EVHPKQHLAK RAFAKPRGPE GKRGHKRLIR GPGENGDDS 349 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TWF2 | 282024 | A2VDX0 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | TWF2 | E2RGD3 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | TWF2 | 102173426 | A0A452EMB1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TWF2 | 11344 | Q6IBS0 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Twf2 | 23999 | Q9Z0P5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | TWF2 | H2QMR1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | 106504190 | A0A4X1VPA1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | TWF2 | G1TX74 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Twf2 | 684352 | B0BMY7 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030175 | filopodium |
| GO:0030426 | growth cone |
| GO:0030027 | lamellipodium |
| GO:0048471 | perinuclear region of cytoplasm |
| GO:0032420 | stereocilium |
| GO:0003785 | actin monomer binding |
| GO:0005524 | ATP binding |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding |
| GO:0005080 | protein kinase C binding |
| GO:0071363 | cellular response to growth factor stimulus |
| GO:0071300 | cellular response to retinoic acid |
| GO:0030837 | negative regulation of actin filament polymerization |
| GO:0045773 | positive regulation of axon extension |
| GO:0010592 | positive regulation of lamellipodium assembly |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51263 | ADF_H |
| Pfam ID | Pfam Term |
|---|---|
| PF00241 | Cofilin_ADF |