Gene: TWF2

Basic information

Tag Content
Uniprot ID A2VDX0
Entrez ID 282024
Genbank protein ID AAI33442.1
Genbank nucleotide ID NM_001105324.2
Ensembl protein ID ENSBTAP00000024225
Ensembl nucleotide ID ENSBTAG00000054131
Gene name TWF2 protein
Gene symbol TWF2
Organism Bos taurus
NCBI taxa ID 9913
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAHQTGIHAT EELKEFFAKA RAGSVRLIKV VIEDEQLVLG AFRELVGCWD QDYDGAVLPL 60
LDAQQPCYLL YRLDSQNAQG FEWLFLAWSP DNSPVRLKML YAATRATVKK EFGGGHIKDE 120
LFGTVKDDLS FAGYQKHLSS CAAPAPLTSA ERELQQIRIN EVKTEISVES KHQTLQGLAF 180
PLQPQAQRAL QQLRQKTINY IQLKLDLERE TIELVHTEPT DVAQLPSRVP RDAARYHFFL 240
YKHTHEGDPL ESVVFIYSMP GYKCSIKERM LYSSCKSRLL DSVEQDFQLE IAKKIEIGDG 300
AELTADFLYD EVHPKQHLAK RAFAKPRGPE GKRGHKRLIR GPGENGDDS 349

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTWF2282024A2VDX0Bos taurusPredictionMore>>
1:1 orthologTWF2E2RGD3Canis lupus familiarisPredictionMore>>
1:1 orthologTWF2102173426A0A452EMB1Capra hircusPredictionMore>>
1:1 orthologTWF211344Q6IBS0Homo sapiensPredictionMore>>
1:1 orthologTwf223999Q9Z0P5CPOMus musculusPublicationMore>>
1:1 orthologTWF2H2QMR1Pan troglodytesPredictionMore>>
1:1 ortholog106504190A0A4X1VPA1Sus scrofaPredictionMore>>
1:1 orthologTWF2G1TX74Oryctolagus cuniculusPredictionMore>>
1:1 orthologTwf2684352B0BMY7Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0003779 actin binding
GO:0030837 negative regulation of actin filament polymerization

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR002108 ADF-H
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR028458 Twinfilin

PROSITE

PROSITE ID PROSITE Term
PS51263 ADF_H

Pfam

Pfam ID Pfam Term
PF00241 Cofilin_ADF