Gene:

Basic information

Tag Content
Uniprot ID A0A4X1VPA1
Entrez ID 106504190
Genbank protein ID
Genbank nucleotide ID XM_013981767.1
Ensembl protein ID ENSSSCP00070043338
Ensembl nucleotide ID ENSSSCG00070025630
Gene name Uncharacterized protein
Gene symbol
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAHQTGIHAT EELKEFFAKA RAGSVRLIKV VIEDEQLVLG ASRELMGCWD QDYDRAVLPL 60
LDAQQPCYLL YRLDTQNAQG FEWLFLAWSP DNSPVRLKML YAATRATVKK EFGGGHIKDE 120
LFGTVKDDLS FAGYQKHLSS CAAPAPLTSA ERELQQIRIN EVKTEISVES KHQTLQGLAF 180
PLQPQAQRAL QQLRQKMINY IQLKLDLERE TIELVHTEPT DVAQLPSRVP RDAARYHFFL 240
YKHTHEGDPL ESVVFIYSMP GYKCSIKERM LYSSCKSRLL DSVEQDFQLE IAKKIEIGDG 300
AELTAEFLYD EVHPKQHAFK QAFAKPKGPG GKRGHKRLIR GPGENGDDS 349

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTWF2282024A2VDX0Bos taurusPredictionMore>>
1:1 orthologTWF2E2RGD3Canis lupus familiarisPredictionMore>>
1:1 orthologTWF2102173426A0A452EMB1Capra hircusPredictionMore>>
1:1 orthologTWF211344Q6IBS0Homo sapiensPredictionMore>>
1:1 orthologTwf223999Q9Z0P5CPOMus musculusPublicationMore>>
1:1 orthologTWF2H2QMR1Pan troglodytesPredictionMore>>
1:1 ortholog106504190A0A4X1VPA1Sus scrofaPredictionMore>>
1:1 orthologTWF2G1TX74Oryctolagus cuniculusPredictionMore>>
1:1 orthologTwf2684352B0BMY7Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0003779 actin binding
GO:0030837 negative regulation of actin filament polymerization

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil

Interpro

InterPro ID InterPro Term
IPR002108 ADF-H
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR028458 Twinfilin

PROSITE

PROSITE ID PROSITE Term
PS51263 ADF_H

Pfam

Pfam ID Pfam Term
PF00241 Cofilin_ADF