| Tag | Content |
|---|---|
| Uniprot ID | A0A452EPR3 |
| Entrez ID | 102178142 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018046999.1 |
| Ensembl protein ID | ENSCHIP00000014177; ENSCHIP00000014163; |
| Ensembl nucleotide ID | ENSCHIG00000015297 |
| Gene name | Uncharacterized protein |
| Gene symbol | GLI3 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEAQSQSSTT TEKKKVENSI VKCPTRPDVS EKAVASSTTS NEDESPGQTY HRERRNAVTM 60 QPQIAPGLSK ISEEPSTSSD ERASLIKKEI HGSLPHLAEP SVPYRGAVFA MDPRNGYMEP 120 HYHPPHLFPA FHPPVPIDAR HHEGRYHYDP SPIPPLHVPS ALSSSPTYSD LPFIRISPHR 180 NPAAASESPF SPPHPYINPY MDYIRSLHSS PSLSMISAAR GLSPTDAPHA GVSPAEYYHQ 240 MALLAGQRSP YADIIPSAAT AGAGALHMEY LHAMDSTRFP SPRLSARPSR KRTLSISPLS 300 DHSFDLQTMI RTSPNSLVTI LNNSRSSSSA SGSYGHLSAS AISPALSFTY PSAPVSLHMH 360 QQILSRQQSL GSAFGHSPPL IHPAPTFPTQ RPIPGIPTVL NPVQVSSGPS ESSQNKPTSE 420 SAVSSTGDLV HNKRSKIKPD EDLPSPGPRG QQEQPEGTTL VKEEGDKDES KQEPEVIYET 480 NCHWEGCSRE FDTQEQLVHH INNDHIHGEK KEFVCRWLDC SREQKPFKAQ YMLVVHMRRH 540 TGEKPHKCTF EGCTKAYSRL ENLKTHLRSH TGEKPYVCEH EGCNKAFSNA SDRAKHQNRT 600 HSNEKPYVCK IPGCTKRYTD PSSLRKHVKT VHGPEAHVTK KQRGDVHPRP PPPRDSGGHS 660 QSRSPGRQTQ GALGEQKDLS NTTSKREECL QVKTVKAEKP MTSQPSPGGQ SSCSSQQSPI 720 SNYSNSGLEL PLTDGGGVGD LSAIDETPVM DSTISTATTA LALQARRNPA GTKWMEHVKL 780 ERLKQVNGML PRLNPILPPK APAVSPLIGN GTQPGTSCSL GGPMPLLPNR SDLSGVDITM 840 LNMLNRRDSS TSTVSSAYLS SRRSSGISPC FSSRRSSEAS QAEGRPQNVS VADSYDPIST 900 DASRRSSEAS QGDGLPSLLS LTPAQQYRLK AKYAAATGGP PPTPLPNMER MSLKTRMALL 960 GDGREPAGTL PPVHPPRRCS DGGAHGYGRR PLLPQDALGN GVRRASDPVR TVSESLSLPR 1020 VQRFNSLNSF NPPVLPPSLE KRNLVLQNYT RPDGGQARHF HSSPCPPSIT ENVTLESLTM 1080 DADVSLNDED LLPDDVVQYL NSQNPAGYEQ HFPGTFSDDS KVPHGLGSVP GDFDPLGLPD 1140 SHASHTGSQQ YRSLEQPCPD ASKSDLPIQW NEVSSGSADL SSSKLKCGQR SMGQQARAFG 1200 SYSHMGVHPQ NPLRSGAGPA GGYPTLGEHA SSFGGLEHLV SHGGGAGTNG NTFHEPPYKA 1260 QQYGNCLNRQ PGAPSLLDGA CGPGIQAVKL KNITMQGSGS HLDFGLSVAP NESTRSTVNG 1320 MPTPDPTGQG YLAQQLLGDS THPQGAGRSG QNLLGQASAT SHIYQGSESS LPGPPSISVQ 1380 PPSVAAVRGY QPCAGYGGGR RQAGPRGGLA LQPGQFSDPS QTCRVNGIKM EMPGQPHQLC 1440 SNVQSYSGQF YDHTVGFGQQ DVKTGSFSMS EANCLLQGAG AENSELLSPG ANQVTSTVDS 1500 LDSHDLEGVQ IDFDAIIDDG DHASLMSGAL SPSIVQNLSH SSSRLTTPRA ALPFPPLSLS 1560 TTNMAIGDMS SLLTSLAEES KFLAVMQ 1587 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | GLI3 | 483244 | J9P1Q3 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | GLI3 | 102178142 | A0A452EPR3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | GLI3 | 2737 | P10071 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Gli3 | 14634 | Q61602 | CPO,CLO | E13.0, E14.0, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | GLI3 | 463369 | H2QUH1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | GLI3 | F1SSD9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | GLI3 | 100355047 | G1SR94 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Gli3 | F1M9H1 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | gli3 | F1QSH8 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0003676 | nucleic acid binding |
| GO:0009952 | anterior/posterior pattern specification |
| GO:0009953 | dorsal/ventral pattern formation |
| GO:0048568 | embryonic organ development |
| GO:0007224 | smoothened signaling pathway |
| Pfam ID | Pfam Term |
|---|---|
| PF00096 | zf-C2H2 |