| Tag | Content |
|---|---|
| Uniprot ID | A0A452EVD0 |
| Entrez ID | 106502734 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018057180.1 |
| Ensembl protein ID | ENSCHIP00000015942 |
| Ensembl nucleotide ID | ENSCHIG00000016385 |
| Gene name | Uncharacterized protein |
| Gene symbol | ZEB1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MADGPRCKRR KQANPRRNNV TNYNTVVETN SDSDDEDKLH IVEEESITDA ADCEGGVPDD 60 DLPSDQTVLP GSSAREGSAK SCWEDDAGKE GQEILGPEAR ADEVGCAVKD DECDSDAENE 120 QNHDPNVEEF LQQQDTAVIY PEAPEDDQRQ GTPEASGHDE NGTPDAFSQL LTCPYCDRGY 180 KRFTSLKEHI KYRHEKNEDN FSCSLCSYTF AYRTQLERHM TSHKSGREQR HVTQSGGNRK 240 FKCTECGKAF KYKHHLKEHL RIHSGEKPYE CPNCKKRFSH SGSYSSHISS KKCISLMPVN 300 GRPRTGLKTS QCPSPSLSAS PGSPTRPQMR QKTENKPLQE QLPVNQIKTE PVDYEFKPIV 360 VASGINCSAP LQNGVFSGGG PLQATSSPQG VVQAVVLPTV GLVSPISINL SDIQNVLKVA 420 VDGNVIRQVL ENNQASLASK EQETINASSI QQGGHSVISA ISLPLVDQDG TTKIIINYSL 480 EQPSQLQVVP QNLKKETPVP TNNCKSEKLP EDLTVKSEKD KSFEGGGNDS TCLLCDDCPG 540 DINALPELKH YDLKQPTQPP RPPTPEAAKP EASAPSGSGD GSLSPSQPPL KNLLSLLKAY 600 YALNAQPSAE ELSKIADSVN LPLDVVKKWF EKMQAGQISV QSSEPSSPEP GKANTPAKSD 660 GQPQAADADE TQDSTGNRQS PLKRASSPVL PGGSAVNGSG SSASSPSPLN LSSSRSAQGY 720 SYPTEGAQEE PQVEPLDLSL PKQQGELLER PTITSVYQNS VYSVQEEPLN LSCAKKEPQK 780 DSCVTDSEPV VNVIPPSANP INIAIPTVTA QLPTIVAIAD QNSVPCLRAL AANKQTILIP 840 QVAYTYSTAV SPAVQETPLK VIQPNGNQDE RQDTSSEGVS NVEDQNDSDS TPPKKKMRKT 900 ENGMYACDLC DKIFQKSSSL LRHKYEHTGK RPHECGICKK AFKHKHHLIE HMRLHSGEKP 960 YQCDKCGKRF SHSGSYSQHM NHRYSYCKRE AEEREPPEPG AAGPGVPPEQ HAGQGDSDER 1020 ESSTREEDED SEKEEEEEEE ERELEELEEE KGSGAARGAE EVEEEVEDGE EEMDDEEDEE 1080 EEAEEEGERA ETEGVGQGAG AGSQAHSLEH KVSEGSEQVS EEKTNEA 1127 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ZEB1 | 477966 | A0A5F4BPF2 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ZEB1 | 106502734 | A0A452EVD0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ZEB1 | 6935 | P37275 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Zeb1 | 21417 | Q64318 | CPO,CLP | E11.5, E12.5, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | ZEB1 | 450387 | K7CJ20 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Zeb1 | F8WG35 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | zeb1b | F1QPM7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005654 | nucleoplasm |
| GO:0003682 | chromatin binding |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0070888 | E-box binding |
| GO:0051216 | cartilage development |
| GO:0071230 | cellular response to amino acid stimulus |
| GO:0007417 | central nervous system development |
| GO:0090103 | cochlea morphogenesis |
| GO:0048596 | embryonic camera-type eye morphogenesis |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0045602 | negative regulation of endothelial cell differentiation |
| GO:0007389 | pattern specification process |
| GO:0045666 | positive regulation of neuron differentiation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0010464 | regulation of mesenchymal cell proliferation |
| GO:0051150 | regulation of smooth muscle cell differentiation |
| GO:0033081 | regulation of T cell differentiation in thymus |
| GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway |
| GO:0048752 | semicircular canal morphogenesis |