CleftGeneDB-Search

Gene: Zeb1

Basic information

Tag	Content
Uniprot ID	F8WG35
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID	ENSRNOP00000024336
Ensembl nucleotide ID	ENSRNOG00000017863
Gene name	Zinc finger E-box-binding homeobox 1
Gene symbol	Zeb1
Organism	Rattus norvegicus
NCBI taxa ID	10116
Cleft type
Developmental stage
Data sources	Homology search
Reference
Functional description
Sequence	VTNYNTVVEA NSDSDDEDKL HIVEEESVTD AADCEGGVPD DELPTDQTVL PGGSDRAGSA 60 KNCWQDDVKD DECDSDAENE QNHDPNVEEF LQQQDTAVIY PEAPEEDQRQ GTPEASGHDD 120 NGTPDAFSQL LTCPYCDRGY KRFTSLKEHI KYRHEKNEDN FSCSLCSYTF AYRTQLERHM 180 TSHKSGREQR HVTQSGGNRK FKCTECGKAF KYKHHLKEHL RIHSGEKPYE CPNCKKRFSH 240 SGSYSSHISS KKCISLMPVN GRPRSGLKTS QCSSPSLSTS PGSPTRPQIR QKIENKPLQE 300 PLSVNQIKTE PVDYEFKPIV VASGINCSTP LQNGVFSGGG QLQATSSPQG VVQAVVLPTV 360 GLVSPISINL SDIQNVLKVA VDGNIIRQVL ENNQASLASK EQEAVSASSI QQGGHSVISA 420 ISLPLVDQDG TTKIIINYSL EQPGQLQVVP QNLKKENPAP PKSCKSEKSP EDLTVKSEKD 480 KSFDGAADES TCLLCEDCPG DLNALPELKH YDPEHPAQPP PPAPATEKPE SSASSAGNGD 540 LSPSQPPLKN LLSLLKAYYA LNAQPSTEEL TKIADSVNLP LDVVKKWFEK MQAGQIPGQS 600 LEPPSPGPGS GNIPKTEEQP QPVDGNEPQE DSTRGQSPLK MTSSPVLPVG SAINGSRSCT 660 SSPSPLNLSS ARNPQGYSCV SEGTQEEPQV EPLDLSLPKQ QGELLERSTV SSVYQNSVYS 720 VQEEPLNLSC AKKEPQKDSC VTDSEPVVNV VPPSANPINI AIPTVTAQLP TIVAIADQNS 780 VPCLRALAAN KQTILIPQVA YTYSATVSPA MQEPPVKVIQ PNGNQDERQD TSSEGVSVED 840 QNDSDCTPPK KKTRKAENGM YACDLCDKIF QKSSSLLRHK YEHTGKRPHE CGICRKAFKH 900 KHHLIEHMRL HSGEKPYQCD KCGKRFSHSG SYSQHMNHRY SYCKRGAEDR DAMEQEDTGP 960 EALPEVLPTE LVGARASPSQ ADSDERESLT REEDEDSEKE EEEEDKEMEE LQEDKECENP 1020 QEEEEEEEEE EEEEEEEEEE EAEEAEHEAA AAKTGGAVEE EAAQQAGSFQ QKASGSESKR 1080 LSEEKTNEA 1089

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

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Relation	Gene symbol	Entrez ID	UniProt ID	Cleft type	Developmental stage	Species	Evidence	Details
1:1 ortholog	Zeb1	21417	Q64318	CPO,CLP	E11.5, E12.5, E13.5, E14.5	Mus musculus	Publication	More>>
1:1 ortholog	ZEB1	477966	A0A5F4BPF2			Canis lupus familiaris	Prediction	More>>
1:1 ortholog	ZEB1	106502734	A0A452EVD0			Capra hircus	Prediction	More>>
1:1 ortholog	ZEB1	6935	P37275			Homo sapiens	Prediction	More>>
1:1 ortholog	ZEB1	450387	K7CJ20			Pan troglodytes	Prediction	More>>
1:1 ortholog	Zeb1		F8WG35			Rattus norvegicus	Prediction	More>>
1:1 ortholog	zeb1b		F1QPM7			Danio rerio	Prediction	More>>

Showing 1 to 7 of 7 entries

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Gene ontology

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GO ID	GO Term
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003682	chromatin binding
GO:0005654	nucleoplasm
GO:0005829	cytosol
GO:0007389	pattern specification process
GO:0007417	central nervous system development
GO:0008285	negative regulation of cell population proliferation
GO:0010464	regulation of mesenchymal cell proliferation
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
GO:0033081	regulation of T cell differentiation in thymus
GO:0045602	negative regulation of endothelial cell differentiation
GO:0045666	positive regulation of neuron differentiation
GO:0045944	positive regulation of transcription by RNA polymerase II
GO:0048596	embryonic camera-type eye morphogenesis
GO:0048704	embryonic skeletal system morphogenesis
GO:0048752	semicircular canal morphogenesis
GO:0051150	regulation of smooth muscle cell differentiation
GO:0051216	cartilage development
GO:0070888	E-box binding
GO:0071230	cellular response to amino acid stimulus