| Tag | Content |
|---|---|
| Uniprot ID | F1QPM7 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000047723 |
| Ensembl nucleotide ID | ENSDARG00000013207 |
| Gene name | Zinc finger E-box-binding homeobox 1b |
| Gene symbol | zeb1b |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MADGPRCKRR KQANPRRTNV SNYSHVLEGQ SDSDDEDKLH IVEEEGSLLD GADCDSVAPD 60 DDPNGTADPD GRWDDVKEEC VSDEDERSRD ALVEEMLQQG DTAVIFPEAP DDEPRQGTPE 120 TSGHDENGTP DSFSQLLTCP YCSRGYKRYT SLKEHIKYRH EKSEDNFSCS LCSYTFAYRT 180 QLDRHMTAHK AGREQRHVTQ SGGGGNRKFK CTECGKAFKY KHHLKEHLRI HSGEKPYECS 240 NCKKRFSHSG SYSSHISSKK CIGLISVNGR PRPSPATGAA KTPQCSSPSL PTSSPTARVQ 300 VRDKLDNSKP LQEQLPLTQI KSEPLDYEYK PVVVAPSARG VNGMFQGGAA APLQGAVQAV 360 VLPTVGLVSP ISINLGDLQN VLKVAVDGNV IRQVLESTQA KGQQAGTGIV GAGGIAQATQ 420 QVIQAISLPI LDQDGNAKIF INYSLDPSQA QAVLQSPKKE PLGSNTEVCK GQKLPEDLTV 480 KTNRDKTTLT VDEKSMLHND ILLKHCGKDE HRINGKNLEE KMDLEGLCPG QPPLKNLLSL 540 LKAYFALNNE PTKEELAKIS ESVSLPAEVV KKWFEKMQLG QISIDPSSPQ HEEEQTTPVD 600 LDGTKGASPK PDLDEQINSE KQEERECCSP AEGIAASVNG IESVPASPSP LNLSADGPVP 660 ARTLEEGEGP LDLSLPKSAT TASVASGHAN TVYSAQEEPL NLTCTKKELL SNASTNAAIY 720 ASQPSANPIN IMTTQLPTLV AITDQGQAQC LRALTTTKQT ILIPQLTYSY TTTSSSPAGT 780 DTPQKNILHV NGIKEEKQEM GSEATSILEE QTDSDSGPTK KKMKRTESGL YACDLCDKIF 840 QKSSSLLRHK YEHTGKRPHE CGICSKAFKH KHHLIEHLRL HSGEKPYQCD KCGKRFSHSG 900 SYSQHMNHRY SYCKKEAQGQ GLGQGVEEED NPGEEQPQTG STATSPPSHL DSDERGSSTR 960 DDESEEEDEM GSGSLVDEDE IQVVKIGEEG DEDDQGADED QERMEEDGDE EGEGETLKVV 1020 VMQDECEEDE NEEDEQTSED AMDTSDHTEE MTERKTPGDN KNIGEHEGNT AAMNGDVK 1078 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ZEB1 | 477966 | A0A5F4BPF2 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | ZEB1 | 106502734 | A0A452EVD0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ZEB1 | 6935 | P37275 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Zeb1 | 21417 | Q64318 | CPO,CLP | E11.5, E12.5, E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | ZEB1 | 450387 | K7CJ20 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Zeb1 | F8WG35 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | zeb1b | F1QPM7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0048856 | anatomical structure development |
| GO:0007369 | gastrulation |
| GO:2000145 | regulation of cell motility |
| GO:0070587 | regulation of cell-cell adhesion involved in gastrulation |
| GO:0010470 | regulation of gastrulation |
| GO:0006357 | regulation of transcription by RNA polymerase II |