| Tag | Content |
|---|---|
| Uniprot ID | A0A452F9C4 |
| Entrez ID | 102171193 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018065663.1; XM_018065662.1; XM_005694866.3; |
| Ensembl protein ID | ENSCHIP00000020830 |
| Ensembl nucleotide ID | ENSCHIG00000019340 |
| Gene name | Uncharacterized protein |
| Gene symbol | MTRR |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRRFLLLYAT QRGQAKAIAE EISEKAVTYG FSADLHCISE SDKYDLKTET APLVMVVSTT 60 GNGDPPDTAR KFVKAIQDKT LPPDFLAHLR YGLLGLGDSE YTYFCNGGKV IDKRLQELGA 120 QRFYDTGHAD DCVGLELVVE PWINGLWAAL EKHFLLNRGR GDMNETLTMA SHASRRTDPM 180 TPELLHVESQ VGLLRLDDSG GKAAEVLEQN AVNSGQSSTL IADFEASLTR SVPALSQASL 240 NIPSLPPEYL EVHLEEALGQ EESHASVSSA DPVFHVPISK AVQLTANDAV KTTLLIELDI 300 SKTDFSYQPG DAFNVICPNS DSEVQFLLQR LQLADRREHR VAMTIKADTR KKGAALPQHV 360 PERCSLQFLL TWCLEIRAVP KKAFLRALAD HTGDSVERRR LQELCSRQGA ADYSRFVRDA 420 SACLSDLLRA FPSCQPPLGL LLEHLPKLQP RLYSCASSSL FHPGKLHFIF NIVEFLSNTT 480 EVVLRRGVCT GWLATLVESI LQPYTCTNHA DGKKALAPKI FISPRTTNSF HLPNDPSVPI 540 IMVGPGAGVA PFIGFLQHRE KLRERHAGGR FGATWLFFGC RHKERDYLFR DELRHFLKCG 600 VLTHLEVSFS RDAAVGEEEG PARYVQDSLQ RHSKQVVGVL LQESGYIYVC GDAKNMAKDV 660 HDALVEIISR ETGAEKLDAM KTLATLKEEK RYLQDIW 697 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MTRR | 507991 | F1MGP5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MTRR | 102171193 | A0A452F9C4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MTRR | 4552 | Q9UBK8 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Mtrr | 210009 | A0A0R4J0G9 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | MTRR | 461717 | H2QQM3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MTRR | F1S0T1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mtrr | 290947 | Q498R1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mtrr | 560667 | F1RE28 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030586 | [methionine synthase] reductase activity |
| GO:0050444 | aquacobalamin reductase (NADPH) activity |
| GO:0071949 | FAD binding |
| GO:0010181 | FMN binding |
| GO:0070402 | NADPH binding |
| GO:0003958 | NADPH-hemoprotein reductase activity |
| GO:0046655 | folic acid metabolic process |
| GO:0043418 | homocysteine catabolic process |
| GO:0009086 | methionine biosynthetic process |
| GO:1904042 | negative regulation of cystathionine beta-synthase activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| InterPro ID | InterPro Term |
|---|---|
| IPR003097 | CysJ-like_FAD-binding |
| IPR017927 | FAD-bd_FR_type |
| IPR001094 | Flavdoxin-like |
| IPR008254 | Flavodoxin/NO_synth |
| IPR001709 | Flavoprot_Pyr_Nucl_cyt_Rdtase |
| IPR029039 | Flavoprotein-like_sf |
| IPR039261 | FNR_nucleotide-bd |
| IPR023173 | NADPH_Cyt_P450_Rdtase_alpha |
| IPR001433 | OxRdtase_FAD/NAD-bd |
| IPR017938 | Riboflavin_synthase-like_b-brl |