| Tag | Content |
|---|---|
| Uniprot ID | F1S0T1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000018117 |
| Ensembl nucleotide ID | ENSSSCG00000017100 |
| Gene name | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
| Gene symbol | MTRR |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRRFLLLYAT QQGQAKAIAE EICEKADAHG FSADLHCISE SDKYDLRTEA APLVVVVSTT 60 GNGDPPDTAR KFVKAIQDKT LPGDLLAHLR YGLLGLGDSE YTYFCNGGKI IDKRLQELGA 120 QHFYDTGHAD DCVGLELVVE PWINGLWAAL EKHFASRRGN EMNGAVAMAS NPSLSSEPVT 180 PEVSHIDSQV GLLRLDDSGR RDSEVSEQNV VNRGPSSVWI AGFESSLTQS APPLSQASLN 240 IPASPPEYLQ VDLQEALGQE ESHAPVTSVD PVFHVPVSKA VQLTTNDAVK TTLLIELDIS 300 QTDFSYQPGD AFSVICPNSD SEVERLLQRL QLADRREHRV FLKIKADTKK KGAALPQHVP 360 EGRSLQFLFT WCLEIRAVPK KAFLRALAEH SSDGAERRRL QELCSRQGTA DYNRLVRDAR 420 ACLLDLLLAF PSCQPPLGLL LEHLPKLQPR PYSCASSSLF HPGKLHFIFN IVEFSSHTTA 480 KVLRRGVCTG WLATLVEPIL QPNARADGEK APAPKIYIAP RTANSFHLPG EPSAPVIMVG 540 PGTGIAPFIG FLQHREKLQE HHPAGHFGAT WLFFGCRHKD RDYLFRDELR HFLKCGILTH 600 LKVSCSREAP AGEEEEAPAK YVQDSIQRHG QQVARALLQE RGYVYVCGDA KNMAKDVNDT 660 LVDIISKEVG GGKLEAMKML ATLKEEKRYL QDIW 694 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MTRR | 507991 | F1MGP5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MTRR | 102171193 | A0A452F9C4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MTRR | 4552 | Q9UBK8 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Mtrr | 210009 | A0A0R4J0G9 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | MTRR | 461717 | H2QQM3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MTRR | F1S0T1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mtrr | 290947 | Q498R1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mtrr | 560667 | F1RE28 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0010181 | FMN binding |
| GO:0016491 | oxidoreductase activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| InterPro ID | InterPro Term |
|---|---|
| IPR003097 | CysJ-like_FAD-binding |
| IPR017927 | FAD-bd_FR_type |
| IPR001094 | Flavdoxin-like |
| IPR008254 | Flavodoxin/NO_synth |
| IPR001709 | Flavoprot_Pyr_Nucl_cyt_Rdtase |
| IPR029039 | Flavoprotein-like_sf |
| IPR039261 | FNR_nucleotide-bd |
| IPR023173 | NADPH_Cyt_P450_Rdtase_alpha |
| IPR001433 | OxRdtase_FAD/NAD-bd |
| IPR017938 | Riboflavin_synthase-like_b-brl |