| Tag | Content |
|---|---|
| Uniprot ID | A0A452FDT3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000022302 |
| Ensembl nucleotide ID | ENSCHIG00000020325 |
| Gene name | Ephrin RBD domain-containing protein |
| Gene symbol | EFNB2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | LAMAARRDSL WKYCWGVLMV LCRTAISRSI VLEPIYWNSS NSKFLPGQGL VLYPQIGDKL 60 DIICPKVDSK TVGQYEYYKV YMVDKDQADR CTIKKENTPL LNCARPDQDV KFTIKFQEFS 120 PNLWGLEFQK NRDYYIISTS NGSLEGLDNQ EGGVCQTRAM KILMKVGQDA SSAGSTRHND 180 PTRRPEFEAG TNGRSSTTSP FVKPNSGSST DGSSAGHSGS NILGSEVALF AGIASGCIIF 240 IVIIITLVVL LLKYRRRHRK HSPQHAATLS LSTLATPKRG GNNNGSEPSD IIIPLRTADS 300 VFCPHYEKVS GDYGHPVYIV QEMPPQSPAN IYYKV 335 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EFNB2 | A0A5F4CFF7 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | EFNB2 | A0A452FDT3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | EFNB2 | 100064730 | B0LDS7 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | EFNB2 | 1948 | P52799 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Efnb2 | 13642 | P52800 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | EFNB2 | 735430 | H2Q7S4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | EFNB2 | G1TLS5 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Efnb2 | 306636 | B2B9A9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | efnb2a | 30219 | O73874 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0098978 | glutamatergic synapse |
| GO:0099061 | integral component of postsynaptic density membrane |
| GO:0098685 | Schaffer collateral - CA1 synapse |
| GO:0046875 | ephrin receptor binding |
| GO:0034332 | adherens junction organization |
| GO:0009887 | animal organ morphogenesis |
| GO:0007155 | cell adhesion |
| GO:0002042 | cell migration involved in sprouting angiogenesis |
| GO:0048013 | ephrin receptor signaling pathway |
| GO:0001945 | lymph vessel development |
| GO:0010839 | negative regulation of keratinocyte proliferation |
| GO:0010977 | negative regulation of neuron projection development |
| GO:0072178 | nephric duct morphogenesis |
| GO:1903849 | positive regulation of aorta morphogenesis |
| GO:2000727 | positive regulation of cardiac muscle cell differentiation |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:1901216 | positive regulation of neuron death |
| GO:0050920 | regulation of chemotaxis |
| GO:0099072 | regulation of postsynaptic membrane neurotransmitter receptor levels |
| GO:0099149 | regulation of postsynaptic neurotransmitter receptor internalization |
| GO:0031295 | T cell costimulation |
| GO:0048845 | venous blood vessel morphogenesis |
| Pfam ID | Pfam Term |
|---|---|
| PF00812 | Ephrin |