| Tag | Content |
|---|---|
| Uniprot ID | H2Q7S4; A0A2J8M9H5; |
| Entrez ID | 735430 |
| Genbank protein ID | JAA02888.1; JAA26050.1; |
| Genbank nucleotide ID | XM_001134800.5 |
| Ensembl protein ID | ENSPTRP00000010233 |
| Ensembl nucleotide ID | ENSPTRG00000006021 |
| Gene name | Ephrin-B2 |
| Gene symbol | EFNB2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAVRRDSVWK YCWGVLMVLC RTAISKSIVL EPIYWNSSNS KFLPGQGLVL YPQIGDKLDI 60 ICPKVDSKTV GQYEYYKVYM VDKDQADRCT IKKENTPLLN CAKPDQDIKF TIKFQEFSPN 120 LWGLEFQKNK DYYIISTSNG SLEGLDNQEG GVCQTRAMKI LMKVGQDASS AGSTRNKDPT 180 RRPELEAGTN GRSSTTSPFV KPNPGSSTDG NSAGHSGNNI LGSEVALFAG IASGCIIFIV 240 IIITLVVLLL KYRRRHRKHS PQHTTTLSLS TLATPKRSGN NNGSEPSDII IPLRTADSVF 300 CPHYEKVSGD YGHPVYIVQE MPPQSPANIY YKV 333 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EFNB2 | A0A5F4CFF7 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | EFNB2 | A0A452FDT3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | EFNB2 | 100064730 | B0LDS7 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | EFNB2 | 1948 | P52799 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Efnb2 | 13642 | P52800 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | EFNB2 | 735430 | H2Q7S4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | EFNB2 | G1TLS5 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Efnb2 | 306636 | B2B9A9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | efnb2a | 30219 | O73874 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0046875 | ephrin receptor binding |
| GO:0007411 | axon guidance |
| GO:0048514 | blood vessel morphogenesis |
| GO:0007155 | cell adhesion |
| GO:0002042 | cell migration involved in sprouting angiogenesis |
| GO:0048013 | ephrin receptor signaling pathway |
| GO:0010977 | negative regulation of neuron projection development |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:1901216 | positive regulation of neuron death |
| GO:0050920 | regulation of chemotaxis |
| Pfam ID | Pfam Term |
|---|---|
| PF00812 | Ephrin |