| Tag | Content |
|---|---|
| Uniprot ID | B2B9A9 |
| Entrez ID | 306636 |
| Genbank protein ID | EDM08786.1; AAY67784.1; |
| Genbank nucleotide ID | NM_001107328.2 |
| Ensembl protein ID | ENSRNOP00000019675 |
| Ensembl nucleotide ID | ENSRNOG00000014648 |
| Gene name | Ephrin B2 |
| Gene symbol | Efnb2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAMARSRRDS VWKYCWGLLM VLCRTAISRS IVLEPIYWNS SNSKFLPGQG LVLYPQIGDK 60 LDIICPKVDS KTVGQYEYYK VYMVDKEQAD RCTIKKENTP LLNCARPDQD VKFTIKFQEF 120 SPNLWGLEFQ KNKDYYIIST SNGSLEGLDN QEGGVCQTRA MKILMKVGQD ASSAGSTRNN 180 DPTRRPELEA GTNGRSSTTS PFVKPNPGSS TDGNSAGHSG NNLLGSEVAL FAGIASGCII 240 FIVIIITLVV LLLKYRRRHR KHSPQHTTTL SLSTLATPKR GGNNNGSEPS DVIIPLRTAD 300 SVFCPHYEKV SGDYGHPVYI VQEMPPQSPA NIYYKV 336 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EFNB2 | A0A5F4CFF7 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | EFNB2 | A0A452FDT3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | EFNB2 | 100064730 | B0LDS7 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | EFNB2 | 1948 | P52799 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Efnb2 | 13642 | P52800 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | EFNB2 | 735430 | H2Q7S4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | EFNB2 | G1TLS5 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Efnb2 | 306636 | B2B9A9 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | efnb2a | 30219 | O73874 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005912 | adherens junction |
| GO:0098978 | glutamatergic synapse |
| GO:0099061 | integral component of postsynaptic density membrane |
| GO:0099056 | integral component of presynaptic membrane |
| GO:0005886 | plasma membrane |
| GO:0098685 | Schaffer collateral - CA1 synapse |
| GO:0046875 | ephrin receptor binding |
| GO:0005102 | signaling receptor binding |
| GO:0034332 | adherens junction organization |
| GO:0009887 | animal organ morphogenesis |
| GO:0007411 | axon guidance |
| GO:0048514 | blood vessel morphogenesis |
| GO:0007155 | cell adhesion |
| GO:0002042 | cell migration involved in sprouting angiogenesis |
| GO:0048013 | ephrin receptor signaling pathway |
| GO:0001945 | lymph vessel development |
| GO:0010839 | negative regulation of keratinocyte proliferation |
| GO:0010977 | negative regulation of neuron projection development |
| GO:0072178 | nephric duct morphogenesis |
| GO:1903849 | positive regulation of aorta morphogenesis |
| GO:2000727 | positive regulation of cardiac muscle cell differentiation |
| GO:0008284 | positive regulation of cell population proliferation |
| GO:1901216 | positive regulation of neuron death |
| GO:0099054 | presynapse assembly |
| GO:0050920 | regulation of chemotaxis |
| GO:0099072 | regulation of postsynaptic membrane neurotransmitter receptor levels |
| GO:0099149 | regulation of postsynaptic neurotransmitter receptor internalization |
| GO:0031295 | T cell costimulation |
| GO:0048845 | venous blood vessel morphogenesis |
| Pfam ID | Pfam Term |
|---|---|
| PF00812 | Ephrin |