Gene: EFNB2

Basic information

Tag Content
Uniprot ID G1TLS5
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSOCUP00000017927
Ensembl nucleotide ID ENSOCUG00000022857
Gene name Ephrin B2
Gene symbol EFNB2
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MMQERPAICL LTLLQHLVLP ATCTSIFERF LPGQGLVLYP QIGDKLDIIC PKVDSKAVGQ 60
YEYYKVYMVD KDQADRCTIK KENTPLLNCA KPDQDVKFTI KFQEFSPNLW GLEFQKNKDY 120
YIISTSNGSL EGLDNQEGGV CQTRAMKILM KVGQDASSAG STRNNDPTRR PELEAGTNGR 180
SSTTSPFVKP NPGSSTDGNS AGHSGNNILG SEVALFAGIA SGCIIFIVII ITLVVLLLRY 240
RRRHRKHSPQ HTTTLSLSTL ATPKRGANNN GSEPSDIIIP LRTADSVFCP HYEKVSGDYG 300
HPVYIVQEMP PQSPANIYYK V 321

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologEFNB2A0A5F4CFF7Canis lupus familiarisPredictionMore>>
1:1 orthologEFNB2A0A452FDT3Capra hircusPredictionMore>>
1:1 orthologEFNB2100064730B0LDS7Equus caballusPredictionMore>>
1:1 orthologEFNB21948P52799Homo sapiensPredictionMore>>
1:1 orthologEfnb213642P52800CPOMus musculusPublicationMore>>
1:1 orthologEFNB2735430H2Q7S4Pan troglodytesPredictionMore>>
1:1 orthologEFNB2G1TLS5Oryctolagus cuniculusPredictionMore>>
1:1 orthologEfnb2306636B2B9A9Rattus norvegicusPredictionMore>>
1:1 orthologefnb2a30219O73874Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0046875 ephrin receptor binding
GO:0048013 ephrin receptor signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0472 Membrane
KW-1185 Reference proteome
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR008972 Cupredoxin
IPR031328 Ephrin
IPR034255 Ephrin-B_Ecto
IPR019765 Ephrin_CS
IPR001799 Ephrin_RBD

PROSITE

PROSITE ID PROSITE Term
PS01299 EPHRIN_RBD_1
PS51551 EPHRIN_RBD_2

Pfam

Pfam ID Pfam Term
PF00812 Ephrin