| Tag | Content |
|---|---|
| Uniprot ID | A0A452FFV0 |
| Entrez ID | 102178659 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018064855.1 |
| Ensembl protein ID | ENSCHIP00000023050 |
| Ensembl nucleotide ID | ENSCHIG00000020790 |
| Gene name | Uncharacterized protein |
| Gene symbol | WFIKKN2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MWALRGCRSW SLWGQGAALL LLLLGVPPRG LALPPLRYSH AGICPNDMNP NLWVDAQSTC 60 KRECETDQEC ETYEKCCPNV CGTKSCVAAR YMDVKGKKGP VGMPKEATCE HFMCLQQGSE 120 CDIWDGQPVC KCRDRCEKEP SFTCASDGLT YYNRCYMDAE ACSKGITLAV VTCRYHFTWP 180 NTSPSPPETT VHPTTAPPET PGLDATAPAL LNHPVHQSVT VGETVSFLCD VVGRPRPEIT 240 WEKQLEDREN VVMRPNHVRG NVVVTNIAQL VIYNAQPQDA GIYTCTARNA AGVLRADFPL 300 SVVSGGQASA TAESSPSGTA FPTAECLKPP DSDDCGEEQV RWYFDAQANN CLTFTFGRCH 360 HNRNHFETYE ACMLACMSGS LAVCSLPALQ GPCKAYAPRW AYNSQTGQCQ SFVYGGCEGN 420 GNNFESREDC EESCPFPRGN QRCRACKPRQ KLVTSFCRSD FVILGRISEL TEEPDSGRAL 480 VTVDEVLKDE KMGLKFLGRE PLEVTLLHMD WTCPCPNVTV GEMPLIIMGE VDGGMAMLRP 540 DSFVGASSTR RARKLREVMH KKTCDVLKDF PGLQ 574 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | WFIKKN2 | 491086 | E2RSS4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN2 | 102178659 | A0A452FFV0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN2 | 124857 | Q8TEU8 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Wfikkn2 | 278507 | Q7TQN3 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | WFIKKN2 | 468405 | A0A2I3T853 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | WFIKKN2 | F1RTB4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | WFIKKN2 | 100345789 | G1SD75 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Wfikkn2 | 287631 | D3Z9K5 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005615 | extracellular space |
| GO:0048019 | receptor antagonist activity |
| GO:0004867 | serine-type endopeptidase inhibitor activity |
| GO:0050431 | transforming growth factor beta binding |
| GO:0048747 | muscle fiber development |
| GO:0043392 | negative regulation of DNA binding |
| GO:0032091 | negative regulation of protein binding |
| GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway |
| GO:0060021 | roof of mouth development |
| GO:0001501 | skeletal system development |
| GO:0007179 | transforming growth factor beta receptor signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR036645 | Elafin-like_sf |
| IPR007110 | Ig-like_dom |
| IPR036179 | Ig-like_dom_sf |
| IPR013783 | Ig-like_fold |
| IPR013098 | Ig_I-set |
| IPR003599 | Ig_sub |
| IPR003598 | Ig_sub2 |
| IPR002350 | Kazal_dom |
| IPR036058 | Kazal_dom_sf |
| IPR002223 | Kunitz_BPTI |
| IPR036880 | Kunitz_BPTI_sf |
| IPR001134 | Netrin_domain |
| IPR018933 | Netrin_module_non-TIMP |
| IPR020901 | Prtase_inh_Kunz-CS |
| IPR008993 | TIMP-like_OB-fold |
| IPR008197 | WAP_dom |
| IPR033639 | WFIKKN2 |