| Tag | Content |
|---|---|
| Uniprot ID | A0A452FPV6 |
| Entrez ID | 102170893 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018059896.1 |
| Ensembl protein ID | ENSCHIP00000026267 |
| Ensembl nucleotide ID | ENSCHIG00000022679 |
| Gene name | ZnMc domain-containing protein |
| Gene symbol | MMP3 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRSLPILLSL CVAVCSAYPL DRAARDKEDS MELVQQYLEN YYNLAKDTKQ FVRRKDSSPV 60 VKKIQEMQKF LGLEVTGKLD SGTLEVIRKP RCGIPDVGSF STFPGMPKWR KTHLTYRIVN 120 YTKDLPRDAV DSAIEKALTV WEKVTPLTFS RIYEGEADIM IIFAVREHGD FLPFDGPGKV 180 LAHAYPPGSG FYGDAHFDDD EQWTKDTSGI NLFLVAAHEF GHSLGLQHST EREALMYPVY 240 DPLTDLARFR LSQDDINGIQ FLYGSPLVSP NDPVVPTESV PPEPGTPAAC DPALSFDAIS 300 TLRGEILFFK GRHFWRKSFR TLEPEFHLIS SFWPSLPSGI DAAYEVTSKD TVFIFKGNQF 360 WAIRGNEMQA GYPRGIHTLG LPSTVRKIDA AFSDKEKKKT YFFAEDKYWR FDEKRQSMEP 420 GFPKQIVEDF PGVEPEVDAV FEVFGFYYFF NGSSQFEFDP NAKKVTHVLK SNSWLNC 477 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MMP3 | 403445 | Q6Y4Q5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | 102170893 | A0A452FPV6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | 100034195 | Q28397 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | 4314 | P08254 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Mmp3 | 17392 | Q922W6 | E12.5, E13.5, E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | MMP3 | 451511 | H2Q4N2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | F1SV58 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mmp3 | F1LPL9 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| GO:0010727 | negative regulation of hydrogen peroxide metabolic process |
| GO:0031334 | positive regulation of protein-containing complex assembly |
| InterPro ID | InterPro Term |
|---|---|
| IPR000585 | Hemopexin-like_dom |
| IPR036375 | Hemopexin-like_dom_sf |
| IPR018487 | Hemopexin-like_repeat |
| IPR018486 | Hemopexin_CS |
| IPR033739 | M10A_MMP |
| IPR024079 | MetalloPept_cat_dom_sf |
| IPR001818 | Pept_M10_metallopeptidase |
| IPR021190 | Pept_M10A |
| IPR021158 | Pept_M10A_Zn_BS |
| IPR006026 | Peptidase_Metallo |
| IPR002477 | Peptidoglycan-bd-like |
| IPR036365 | PGBD-like_sf |