| Tag | Content |
|---|---|
| Uniprot ID | F1SV58 |
| Entrez ID | |
| Genbank protein ID | HDA50741.1; HCZ81364.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000015910 |
| Ensembl nucleotide ID | ENSSSCG00000014985 |
| Gene name | Stromelysin-1 |
| Gene symbol | MMP3 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRKLPVLLLL CVAVCSSYPV DRAAVDKDDS MDFVQKYLED YYNLTKDVKQ VVRRKDSSLV 60 VKKIQEMQKF LGLEVTGKLD SNTLEVMHKP RCGVPDVGYF STFPGLPKWR KNDLTYRIVN 120 YTLDLPRSVI DSTIEKALKI WEEVTPLTFS KISEGEADIM ITFAVREHGD FSPFDGPGKV 180 LAHAYAPGPG IYGDAHFDDD EQWTKDTSGV NLFLVAAHEL GHSLGLFHST DSNALMYPVY 240 NPLTDLARFR LSQDDVNGIQ SLYGPPPASP PEPVEPTEST PPEPGTPATC DPALSFDAIS 300 TLRGEILFFK DRHFWRKSFR RLEPEFHLIS SFWPPLPSSI DAACEVISKD TVFIFKGTQF 360 WAIRGNDVQP GYPRSIHTLG FPSTVKKIDA AISDKETKKT YFFVEDKYWR FDEKRQSMEP 420 GFPKQIVEDF PGVEPKVDAV FEAFGFFYFF NGSSQFEFDP NAKKVTHVLK SNKWLNC 477 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MMP3 | 403445 | Q6Y4Q5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | 102170893 | A0A452FPV6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | 100034195 | Q28397 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | 4314 | P08254 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Mmp3 | 17392 | Q922W6 | E12.5, E13.5, E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | MMP3 | 451511 | H2Q4N2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | F1SV58 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mmp3 | F1LPL9 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| GO:0010727 | negative regulation of hydrogen peroxide metabolic process |
| GO:0031334 | positive regulation of protein-containing complex assembly |
| InterPro ID | InterPro Term |
|---|---|
| IPR000585 | Hemopexin-like_dom |
| IPR036375 | Hemopexin-like_dom_sf |
| IPR018487 | Hemopexin-like_repeat |
| IPR033739 | M10A_MMP |
| IPR024079 | MetalloPept_cat_dom_sf |
| IPR001818 | Pept_M10_metallopeptidase |
| IPR021190 | Pept_M10A |
| IPR021158 | Pept_M10A_Zn_BS |
| IPR006026 | Peptidase_Metallo |
| IPR002477 | Peptidoglycan-bd-like |
| IPR036365 | PGBD-like_sf |