Gene: Mmp3

Basic information

Tag Content
Uniprot ID Q922W6
Entrez ID 17392
Genbank protein ID AAH06725.1; AAO37583.1;
Genbank nucleotide ID NM_010809.2
Ensembl protein ID ENSMUSP00000034497
Ensembl nucleotide ID ENSMUSG00000043613
Gene name Matrix metallopeptidase 3
Gene symbol Mmp3
Organism Mus musculus
NCBI taxa ID 10090
Cleft type
Developmental stage E12.5, E13.5, E14.5
Data sources Homology search
Reference
Functional description
Sequence
MKMKGLPVLL WLCVVVCSSY PLHDSARDDD AGMELLQKYL ENYYGLAKDV KQFIKKKDSS 60
LIVKKIQEMQ KFLGLEMTGK LDSNTMELMH KPRCGVPDVG GFSTFPGSPK WRKSHITYRI 120
VNYTPDLPRQ SVDSAIEKAL KVWEEVTPLT FSRISEGEAD IMISFAVGEH GDFVPFDGPG 180
TVLAHAYAPG PGINGDAHFD DDERWTEDVT GTNLFLVAAH ELGHSLGLYH SAKAEALMYP 240
VYKSSTDLSR FHLSQDDVDG IQSLYGTPTA SPDVLVVPTK SNSLEPETSP MCSSTLFFDA 300
VSTLRGEVLF FKDRHFWRKS LRTPEPEFYL ISSFWPSLPS NMDAAYEVTN RDTVFIFKGN 360
QFWAIRGHEE LAGYPKSIHT LGLPATVKKI DAAISNKEKR KTYFFVEDKY WRFDEKKQSM 420
EPGFPRKIAE DFPGVDSRVD AVFEAFGFLY FFSGSSQLEF DPNAKKVTHI LKSNSWFNC 479

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Gene expression information

Gene expression during embryonic days (E11.5~E18.5) ~ adult days (Ps) in the lip and palate tissues. (X-axis: days, Y-axis: tissues)

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Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Identified variants/mutations related to cleft phenotype

Other genetic variants/mutations

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Gene Ontology (GO)/biological pathways

GO:Molecular Function


GO:Biological Process


GO:Cellular Component


Reactome Pathway

Functional annotations

Keywords

Interpro

PROSITE

Pfam