| Tag | Content |
|---|---|
| Uniprot ID | F1LPL9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000012310 |
| Ensembl nucleotide ID | ENSRNOG00000032626 |
| Gene name | Stromelysin-1 |
| Gene symbol | Mmp3 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MKGLPVLLWL CTAVCSSYPL HGSEEDAGME VLQKYLENYY GLEKDVKQFL LHQISSPEVR 60 ELIHLQKFLR ILVAGKLDSR IQNYLHELNC GHQDSPAFSL FPRKDKWRKG HIPKRCSNIK 120 SQMPEKQEAP RTQRDVWEEV TPLTFSRISE GEADIMISFA VEEHGDFIPF DGPGMVLAHA 180 YAPGPGINGD AHFDDDERWT DDVTGTNLFL VAAHELGHSL GLFHSANAEA LMYPVYKSST 240 DLARFHLSQD DVDGIQSLYG PPTESPDVLV VPTKSNSLDP ETLPMCSSAL SFDAVSTLRG 300 EVLFFKDRHF WRKSLRTPEP GFYLISSFWP SLPSNMDAAY EVTNRDTVFI LKGNQIWAIR 360 GHEELAGYPK SIHTLGLPET VQKIDAAISL KDQKKTYFFV EDKFWRFDEK KQSMDPGFPR 420 KIAENFPGIG TKVDAVFEAF GFLYFFSGSS QLEFDPNAGK VTHILKSNSW FNC 473 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MMP3 | 403445 | Q6Y4Q5 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | 102170893 | A0A452FPV6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | 100034195 | Q28397 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | 4314 | P08254 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Mmp3 | 17392 | Q922W6 | E12.5, E13.5, E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | MMP3 | 451511 | H2Q4N2 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MMP3 | F1SV58 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mmp3 | F1LPL9 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| GO:0010727 | negative regulation of hydrogen peroxide metabolic process |
| GO:0031334 | positive regulation of protein-containing complex assembly |