| Tag | Content |
|---|---|
| Uniprot ID | A0A452FUL3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000028050 |
| Ensembl nucleotide ID | ENSCHIG00000023721 |
| Gene name | Fork-head domain-containing protein |
| Gene symbol | FOXP2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTRQALCSFT LVELLPETKL CVCGHSSGDG HPHNTFAVPV SVAMMTPQVI TPQQMQQILQ 60 QQVLSPQQLQ ALLQQQQAVM LQQQQLQEFY KKQQEQLHLQ LLQQQQQQQQ QQQQQQQQQQ 120 QQQQQQQQQQ QQQQQPQQQH PGKQAKEQQQ QQLAAQQLVF QQQLLQMQQL QQQQHLLSLQ 180 RQGLISIPPG QAALPVQSLP QAGLSPAEIQ QLWKEVTGVH SMEDNGIKHG GLDLTTNNSS 240 STTSSTTSKA SPPITHHTIV NGQSSVLNAR RDSSSHEETG ASHTLYGHGV CKWPGCESIC 300 EDFGQFLKHL NNEHALDDRS TAQCRVQMQV VQQLEIQLSK ERERLQAMMT HLHMRPSEPK 360 PSPKPLNLVS SVTMSKNMLE TSPQSLPQTP TTPTAPVTPI TQGPSVITPA SVPNVGAIRR 420 RHSDKYNIPM SSEIAPNYEF YKNADVRPPF TYATLIRQAI MESSDRQLTL NEIYSWFTRT 480 FAYFRRNAAT WKNAVRHNLS LHKCFVRVEN VKGAVWTVDE VEYQKRRSQK ITGSPTLVKN 540 IPTSLGYGAA LNASLQAALA ESSLPLLSNP GLINNASSGL LQAVHEDLNG SLDHIDSNGN 600 SSPGCSPQPH IHSIHVKEEP VIAEDEDCPM SLVTTANHSP ELEDDREIEE EPLSEDLE 658 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FOXP2 | A0A452FUL3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FOXP2 | 93986 | O15409 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Foxp2 | 114142 | P58463 | E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | FOXP2 | 449627 | Q8MJA0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FOXP2 | A0A5G2QN29 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Foxp2 | 500037 | P0CF24 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | foxp2 | H0WFE7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0042803 | protein homodimerization activity |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0043010 | camera-type eye development |
| GO:0021757 | caudate nucleus development |
| GO:0021549 | cerebellum development |
| GO:0021987 | cerebral cortex development |
| GO:0048286 | lung alveolus development |
| GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis |
| GO:0002053 | positive regulation of mesenchymal cell proliferation |
| GO:0009791 | post-embryonic development |
| GO:0021758 | putamen development |
| GO:0060013 | righting reflex |
| GO:0007519 | skeletal muscle tissue development |
| GO:0048745 | smooth muscle tissue development |
| GO:0042297 | vocal learning |