Gene: FOXP2

Basic information

Tag Content
Uniprot ID A0A5G2QN29
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000066297
Ensembl nucleotide ID ENSSSCG00000016639
Gene name Forkhead box P2
Gene symbol FOXP2
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MMTPQVITPQ QMQQILQQQV LSPQQLQALL QQQQAVMLQQ QQLQEFYKKQ QEQLHLQLLQ 60
QQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQQHPGK QAKEQQQQQQ QLAAQQLVFQ 120
QQLLQMQQLQ QQQHLLSLQR QGLISIPPGQ AALPVQSLPQ AGLSPAEIQQ LWKEVTGVHS 180
MDDNGIKHGG LDLTTNNSSS TTSSTTSKAS PPITHHSIVN GQSSVLNARR DSSSHEETGA 240
SHTLYGHGVC KWPGCESICE DFGQFLKHLN NEHALDDRST AQCRVQMQVV QQLEIQLSKE 300
RERLQAMMTH LHMRPSEPKP SPKPLNLVSS VTMSKNMLET SPQSLPQTPT TPTAPVTPIT 360
QGPSVITPAS VPNVGAIRRR HSDKYNIPMS SEIAPNYEFY KNADVRPPFT YATLIRQAIM 420
ESSDRQLTLN EIYSWFTRTF AYFRRNAATW KNAVRHNLSL HKCFVRVENV KGAVWTVDEV 480
EYQKRRSQKI TGSPTLVKNI PTSLGYGAAL NASLQAALAE SSLPLLSNPG LINNASSGLL 540
QAVHEDLNGS LDHLDSNGNS SPGCSPQPHI HSIHVKEEPV MAEDEDCPMS LVTTANHSPE 600
LEDDREIEEE PLSEDLE 617

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologFOXP2A0A452FUL3Capra hircusPredictionMore>>
1:1 orthologFOXP293986O15409Homo sapiensPublicationMore>>
1:1 orthologFoxp2114142P58463E14.5Mus musculusPredictionMore>>
1:1 orthologFOXP2449627Q8MJA0Pan troglodytesPredictionMore>>
1:1 orthologFOXP2A0A5G2QN29Sus scrofaPredictionMore>>
1:1 orthologFoxp2500037P0CF24Rattus norvegicusPredictionMore>>
1:1 orthologfoxp2H0WFE7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0238 DNA-binding
KW-0539 Nucleus
KW-1185 Reference proteome
KW-0804 Transcription

Interpro

InterPro ID InterPro Term
IPR001766 Fork_head_dom
IPR032354 FOXP-CC
IPR030456 TF_fork_head_CS_2
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS00658 FORK_HEAD_2
PS50039 FORK_HEAD_3

Pfam

Pfam ID Pfam Term
PF00250 Forkhead
PF16159 FOXP-CC