| Tag | Content |
|---|---|
| Uniprot ID | H0WFE7 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000125579 |
| Ensembl nucleotide ID | ENSDARG00000005453 |
| Gene name | Forkhead box P2 |
| Gene symbol | foxp2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MMSPQVITPQ QMQQILQQQV LSPQQLQALL QQQQAVMLQQ QHLQEFYKKQ QEQLHLQLLQ 60 QQHPGKQAKE QQQQQQQLAA QQLVFQQQLL QMQQLQQQQH LLNMQRQGLL SMPPGPGQPT 120 LPGQTLPPAG LSPAELQQLW KDVTASHTME DNGMKHSGLD LSTNNNTSTT STSNPKASPP 180 ITHHSMSNGQ SPALNNNRRE SSLHEETAVS HSLYGHGVCK WPGCESICDD FGQFLKHLNN 240 EHALDDRSTA QCRVQMQVVQ QLEIQLSKER ERLQAMMAHL HMRPSEPKPS PKPLNLVSSV 300 TMSKNLPSIS PPNLPQTPTT PTAPVTPLSQ MPQVPNVLSP ANVPSMGAMR RRHTDKYSMA 360 LSSEIAPNYE FYKNADVRPP FTYATLIRQA IMESSDMQLT LNEIYSWFTR TFAYFRRNAA 420 TWKNAVRHNL SLHKCFVRVE NVKGAVWTVD EMEYQKRRSQ KITGSPTLVK NLPSSLGYGA 480 ALNASLQAAL AETTLPLLGN PGLMNSASAM MGASPPVMMS GSPTGLLQGT THEELNGTLD 540 HLDTNGHSSP GYSPHTHLPP IHVKEEPLNM EDEDCPMSLV TTANHSPELD DDRELEEGNL 600 SEDLE 605 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FOXP2 | A0A452FUL3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FOXP2 | 93986 | O15409 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Foxp2 | 114142 | P58463 | E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | FOXP2 | 449627 | Q8MJA0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | FOXP2 | A0A5G2QN29 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Foxp2 | 500037 | P0CF24 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | foxp2 | H0WFE7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0046872 | metal ion binding |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0045471 | response to ethanol |