| Tag | Content |
|---|---|
| Uniprot ID | A0A452G485 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000031316 |
| Ensembl nucleotide ID | ENSCHIG00000025716 |
| Gene name | Uncharacterized protein |
| Gene symbol | DVL2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAGSGAGGGG VGETKVIYHL DEEETPYLVK IPVPAERITL GDFKSVLQRP AGAKYFFKSM 60 DQDFGVVKEE ISDDNARLPC FNGRVVSWLV SSDNPQPEMA PPAHEPRTDL APPPPPLPPL 120 PPERTSGIGD SRPPSFHPNV SSSRENLEPE TETESVVSLR RERPRRRDSS EHGAGGHRPS 180 GPSRLERHLA GYESSSTLMT SELESTSSSD LPRALAPLPV LSFGPMTTAR PPRAGRIWSL 240 GSLGGMQLAL PLITWLPSTE KYNFLGISIV GQSNERGDGG IYIGSIMKGG AVAADGRIEP 300 GDMLLQVNDM NFENMSNDDA VRVLRDIVHK PGPIVLTVAK CWDPSPQAYF TLPRNEPIQP 360 IDPAAWVSHS AALTGTFPAY PGSSSMSTIT SGSSLPDGCE GRGLSIHTDM ASVTKAMAAP 420 ESGLEVRDRM WLKITIPNAF LGSDVVDWLY HHVEGFPERR EARKYASGLL KAGLIRHTVN 480 KITFSEQCYY VFGDLSGGCE SYLVNLSLND NDGSSGASDQ DTLAPLPGAT PWPLLPTFSY 540 QYPAPHPYSP QPPPYHELSS YTYGGGSASS QHSEGSRSSG STRSDGGAGR TGRPEDRAPE 600 SKSGSGSESE PSSRGGSLRR GGEPGGTGDG GPPPSRGSSG GAPNLRAHPG LHPYGPPPGM 660 ALPYNPMMVV MMPPPPPPVP PAVQPPGAPP VRDLGSVPPE LTASRQSFHM AMGNPSEFFV 720 DVM 723 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DVL2 | A0A452G485 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | DVL2 | 1856 | O14641 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Dvl2 | 13543 | Q60838 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | DVL2 | 455236 | H2QC24 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | DVL2 | A0A287AJQ6 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Dvl2 | 303251 | D3ZB71 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | dvl2 | F1QM97 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0035556 | intracellular signal transduction |
| GO:0016055 | Wnt signaling pathway |
| InterPro ID | InterPro Term |
|---|---|
| IPR000591 | DEP_dom |
| IPR024580 | Dishevelled_C-dom |
| IPR008339 | Dishevelled_fam |
| IPR003351 | Dishevelled_protein_dom |
| IPR001158 | DIX |
| IPR038207 | DIX_dom_sf |
| IPR015506 | Dsh/Dvl-rel |
| IPR008341 | DVL2 |
| IPR001478 | PDZ |
| IPR036034 | PDZ_sf |
| IPR029071 | Ubiquitin-like_domsf |
| IPR036388 | WH-like_DNA-bd_sf |
| IPR036390 | WH_DNA-bd_sf |