| Tag | Content |
|---|---|
| Uniprot ID | B0UYB0 |
| Entrez ID | |
| Genbank protein ID | AAI62512.1 |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000034047 |
| Ensembl nucleotide ID | ENSDARG00000027234 |
| Gene name | Intraflagellar transport 88 homolog |
| Gene symbol | ift88 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MENVHLVPEE EEDDLYTGYN DYNPTFDSED LHNDVAFQQA VRTSHGRRPP MTAKYPGTAI 60 GGRPIGTAYG SRVPIGTAMG RPMTGAVQDG AARPMTAVRA AGYSSSIARG SAFDPLGQAK 120 GPAPPLETKN EDTPEEKIKI LEKKVNDLIE DSCLAHARGD LQVSLEKAKE AGRKERALVR 180 QREQTGTADH INLDLTYSVL FNLANQYANN DMYTEALNTY QVIVKNKMFN NAGRLKVNMA 240 NIYFKQKNYT KAIKFYRMAL DQISNAHNAM RIKIMQNIGV VFIHMGQYSD AITSFEYIMT 300 ESPNIKTGFN LILCYYAIGD RERMKKAFQK LICVPLGVDD DDKYIPPNDD PHANMVIEAI 360 KNDKLHQMER ERKALAEKYI MTSAKLIAPA IEMSFAAGFD WCVDMVKGSQ YVELANDLEI 420 NKAITYLRQR DFKQAVETLK MFEKKDSRVK SAAATNLSFL YFLEKDFDQA DRYAELAMSA 480 DRYNPAALIN KGNTLFVKED YEKAAEFYKE SLRNDSSCTE ALYNLGLTYK RLGRLEEALD 540 CFLKLHAILR NSAQVMYQLA NLYEMLEDPH QAIEWLMQLT SVTPTDAQVL AKLGDLYDNE 600 GDKSQAFQYY YESYRYFPSN ISVIEWLGAY YIDTQFCEKA IQYFERATLI QPTQVKWQLM 660 VASCYRRSGN YQKALETYKE IHRKFPENVE CLRFLVRLCT DMGLKEVQDY ATKLKKVEKM 720 KEIREQRVRS GRDSSARSRR EGSAGSDSGQ SNHGTSAKSE RLSVKLKTLP GSNEPYEAST 780 QQEIDASYVD PLGPQTQRPK TAARKRNEED EFADEELGDD LLPE 824 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | IFT88 | 514177 | E1BLX1 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | IFT88 | 477345 | E2R838 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | IFT88 | A0A452FFN1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | IFT88 | 8100 | Q13099 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ift88 | 21821 | Q61371 | CPO,CLP,CLO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | IFT88 | A0A2I3RWX3 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | I3LER9 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | IFT88 | 100009576 | G1SJN9 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Ift88 | 305918 | A0A096MK92 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ift88 | B0UYB0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005930 | axoneme |
| GO:0005814 | centriole |
| GO:0036064 | ciliary basal body |
| GO:0097546 | ciliary base |
| GO:0005929 | cilium |
| GO:0005576 | extracellular region |
| GO:0031514 | motile cilium |
| GO:0097730 | non-motile cilium |
| GO:0019894 | kinesin binding |
| GO:0071482 | cellular response to light stimulus |
| GO:0090660 | cerebrospinal fluid circulation |
| GO:0060271 | cilium assembly |
| GO:0007368 | determination of left/right symmetry |
| GO:0003351 | epithelial cilium movement involved in extracellular fluid movement |
| GO:0000132 | establishment of mitotic spindle orientation |
| GO:0042462 | eye photoreceptor cell development |
| GO:0007369 | gastrulation |
| GO:0002244 | hematopoietic progenitor cell differentiation |
| GO:0060122 | inner ear receptor cell stereocilium organization |
| GO:0042073 | intraciliary transport |
| GO:0001822 | kidney development |
| GO:1905515 | non-motile cilium assembly |
| GO:0007219 | Notch signaling pathway |
| GO:0045494 | photoreceptor cell maintenance |
| GO:0045880 | positive regulation of smoothened signaling pathway |
| GO:0072019 | proximal convoluted tubule development |
| GO:0060785 | regulation of apoptosis involved in tissue homeostasis |