Gene: IFT88

Basic information

Tag Content
Uniprot ID E2R838
Entrez ID 477345
Genbank protein ID
Genbank nucleotide ID XM_534539.6
Ensembl protein ID ENSCAFP00000010791
Ensembl nucleotide ID ENSCAFG00000007250
Gene name Intraflagellar transport 88
Gene symbol IFT88
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MMQNVHLAPE TDEDDLYSGY NDYNPTYDTE ELENDTAFQQ AVRTSHGRRP PITAKIPSTA 60
VTRPVATGYG SKTSLASSMG RPMTGAIQDG VTRPMTAVRA AGFTKAALRG SAFDPLGQSR 120
GPAPPLEAKN EDSPEEKIRQ LEKKVNELVE ESCIANSCGD LKLALEKAKD AGRKERILVR 180
QREQVTTPEN INLDLTYSVL LNLASQYSAN EMYAEALTTF QVIVKNKMFS NAGRLKVNMG 240
NIYLKQRNYS KAIKFYRMAL DQIPSVHKEM RIKIMQNIGV TFIKTGQYSD AINSFEHIMS 300
MAPNLKAGFN LILSYFAVGD RDKMKKAFQK LIAVPLEIDE DDKYISPSDD PHTNLVIEAI 360
KNDRLRQMER ERKAMAEKYI MTAAKLIAPV IETSFAVGYD WCVEVVKASQ YVELANDLEI 420
NKAITYLRQK DFNQAVETLK MFEKKDSRVK SAAATNLSFL YYLENEFAQA SSYADLAVNS 480
DRYNPSALTN KGNTVFANGD YEKAAEFYKE ALRNDSSCTE ALYNIGLTYK RLNRLDEALD 540
CFLKLHTILR NSAQVLYQIA NVYELMEDPH QAIEWLMQLI SVVPTDSRAL SKLGELYDSE 600
GDKSQAFQYY YESYRYFPSN IEVIEWLGAY YIDTQFCEKA IQYFERASLI QPTQVKWQLM 660
VASCFRRSGN YQKALDTYKD IHRKFPENVE CLRFLVRLCT DIGLKEVQEY ATKLKRLEKM 720
KEIREQRIKS GRDGSGGPRS RREGSASSDS GQNCSASSKG ERLSAKLRAL PGTNEPYESS 780
SNKEIDASYV DPLGPQIERP KTAAKKRIDE DDFADEELGD DLLPE 825

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologIFT88514177E1BLX1Bos taurusPredictionMore>>
1:1 orthologIFT88477345E2R838Canis lupus familiarisPredictionMore>>
1:1 orthologIFT88A0A452FFN1Capra hircusPredictionMore>>
1:1 orthologIFT888100Q13099Homo sapiensPredictionMore>>
1:1 orthologIft8821821Q61371CPO,CLP,CLOMus musculusPublicationMore>>
1:1 orthologIFT88A0A2I3RWX3Pan troglodytesPredictionMore>>
1:1 orthologI3LER9Sus scrofaPredictionMore>>
1:1 orthologIFT88100009576G1SJN9Oryctolagus cuniculusPredictionMore>>
1:1 orthologIft88305918A0A096MK92Rattus norvegicusPredictionMore>>
1:1 orthologift88B0UYB0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005814 centriole
GO:0005813 centrosome
GO:0036064 ciliary basal body
GO:0097546 ciliary base
GO:0097730 non-motile cilium
GO:0019894 kinesin binding
GO:0060122 inner ear receptor cell stereocilium organization
GO:0042073 intraciliary transport
GO:0001822 kidney development
GO:1905515 non-motile cilium assembly

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0802 TPR repeat

Interpro

InterPro ID InterPro Term
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

PROSITE

PROSITE ID PROSITE Term
PS50005 TPR
PS50293 TPR_REGION

Pfam

Pfam ID Pfam Term
PF13174 TPR_6
PF13181 TPR_8