Gene: Phc2

Basic information

Tag Content
Uniprot ID D4A0M3
Entrez ID 313038
Genbank protein ID EDL80507.1
Genbank nucleotide ID XM_006238926.3; NM_001013169.2;
Ensembl protein ID ENSRNOP00000059238
Ensembl nucleotide ID ENSRNOG00000006004
Gene name Polyhomeotic homolog 2
Gene symbol Phc2
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MENELPVPHT SSRASITTNT SGTNSSSGCS SSSGGGSGRP TAPQISVYSG IPDRQTVQVI 60
QQALHRQPST AAQYLQQMYA AQQQHLMLQT AALQQQHLSS AQLQSLAAVQ QASLVANRQG 120
STSGSSVSSQ APAQSSSLNL AASPAAAQLI NRAQSVNSAT ASGLAQQAVL LGNTSSPALT 180
ASQAQMYLRA QMLIFTPTAT VATVQPELGT GSPARPPTPA QVQNLTLRTQ QTPAAAAAAA 240
ASGPAPTQPV LPSLALKPTP SSSQPLPPTP QGRTVVQGSP VGAKPSVTDN VTEPLKTDGN 300
SNMEARPGPD RATVPTVATH QLTAPAYTQL QPHQLLPQPS SKHPQPQFVA QQQPQPPRPT 360
PQVQSQPQLA AVSPSLALQP SPEGHAMPLG PVTQALPLQC STAHVHKPGS SQQCHLPTPD 420
SGSQNGHPEG VSHAPQRRFQ HTSAVILQLQ PASPVPQQCA PDDWKEVVPA EKSVPVTRPG 480
LSPHQQAIIT AIPGGLPGPK SPNIQQCPAH ETGQGIVHAL TDLSSPGMTS GNGNSASSIT 540
GTAPQNGENK PPQAIVKPQI LTHVIEGFVI QEGAEPFPVG RSSLLVGNLK KKYAQGFLPE 600
KLPQQDHTTT TDSEMEEPYL QESKEEGTPL KLKCELCGRV DFAYKFKRSK RFCSMACAKR 660
YNVGCTKRVG LFHSDRSKLQ KAGTTTHNRR RASKASLPTL TKDTKKQPSG TVPLSVTAAL 720
QLAHSQEDSS RCSDNSSYEE PLSPISASSS TSRRRQGQRD LELSDMHMRD LVGMGHHFLP 780
SEPTKWNVED VYEFIRSLPG CQEIAEEFRA QEIDGQALLL LKEDHLMSAM NIKLGPALKI 840
YARISMLKDS

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPHC2537511E1BFG7Bos taurusPredictionMore>>
1:1 orthologPHC2487297J9P8A4Canis lupus familiarisPredictionMore>>
1:1 orthologPHC2A0A452F0Q9Capra hircusPredictionMore>>
1:1 orthologPHC21912Q8IXK0Homo sapiensPredictionMore>>
1:1 orthologPhc254383Q9QWH1CPOMus musculusPublicationMore>>
1:1 orthologPHC2456729H2PYL7Pan troglodytesPredictionMore>>
1:1 orthologPHC2I3LIR0Sus scrofaPredictionMore>>
1:1 orthologPHC2100351541G1T576Oryctolagus cuniculusPredictionMore>>
1:1 orthologPhc2313038D4A0M3Rattus norvegicusPredictionMore>>
1:1 orthologphc2b394177F6P2R0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0000792 heterochromatin
GO:0005654 nucleoplasm
GO:0005634 nucleus
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
GO:0042802 identical protein binding
GO:0008270 zinc ion binding
GO:0007283 spermatogenesis

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR001660 SAM
IPR013761 SAM/pointed_sf
IPR012313 Znf_FCS
IPR038603 Znf_FCS_sf

PROSITE

PROSITE ID PROSITE Term
PS50105 SAM_DOMAIN
PS51024 ZF_FCS

Pfam

Pfam ID Pfam Term
PF00536 SAM_1