| Tag | Content |
|---|---|
| Uniprot ID | F6P2R0 |
| Entrez ID | 394177 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_201202.3 |
| Ensembl protein ID | ENSDARP00000018055 |
| Ensembl nucleotide ID | ENSDARG00000013224 |
| Gene name | Polyhomeotic homolog 2b (Drosophila) |
| Gene symbol | phc2b |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGLTTGPNGA RAAPQKSLRR VWQRGSRGSK VKHRGGTMEG EQSTPAASAS STTGTSTSTT 60 NSTGTTSAST ASTASSTSSS TSSARQAVPQ ISVYSGIPDR QTVQVIQQAL NRQPSTAAQY 120 LQQMYAAQQQ HLMLQTAALQ QQHLSTAQLQ SLAAVQQASL AAGRQSSNQN GTSSTQSGSS 180 QTTINLTTSP AAAQLISRAQ SVNSAPSGIS QQAVLLGNAS SSTLTASQAQ MYLRAQMAQQ 240 SNLVHVARSL GRAVPLSSQL ILAPTATVTA LQSDTNTTNN TQSASAQVQN LALRNHQGVS 300 STPQATGLQA LSLKQTPVSI QPTPLIKTPS QSTGAGKNNL NAASSDGVKK AEEGQTEMKA 360 VNMSRNVSSS HPLIAPAYAQ IQPQALIKQQ PQQFVIQPQA TPTSRSQPQL LQTASIQPHQ 420 QTASLGIPSS AQTSTVTGII PVLPKPALHN QGSAQTQQAT IFHSTVSHHA HTALAHAKAQ 480 PVQLTAINLQ IQPAQNQASR LAQDDKEKPT SLVLREICPP VQIHPSTTTQ GTDPPEQSKA 540 DTVNATSQTQ GSVETAREPT GAQLTSSMTS AVSSEPPPAA VMGNTTQNGE NKPPQAIVKP 600 HVLTHVIEGF VIQEGAEPFP VERPPVAAES PKKPDTQLPS DPEKTASSNS LSATNSDTEE 660 AGQQDTRVEE ETEKPKLTCE LCGWVDFAHK FKRSKRFCSM VCAKRYSVSC TKRVGLFRPD 720 RTKSTNQINQ WRRRRSHSPR GREAKKQRLS VSQQSQGESI SSPLQSQPSQ GESSPCSDIS 780 SYEEATSPLS AASSGPVVSQ GVVAANEPEE LPLLSQHFLP CDPTKWNVQE VFEFIRSLPG 840 CQEIADEFRA QEIDGQALLL LKEDHLMSAM NIKLGPALKI FARINMLKDS |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PHC2 | 537511 | E1BFG7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PHC2 | 487297 | J9P8A4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PHC2 | A0A452F0Q9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PHC2 | 1912 | Q8IXK0 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Phc2 | 54383 | Q9QWH1 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PHC2 | 456729 | H2PYL7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PHC2 | I3LIR0 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | PHC2 | 100351541 | G1T576 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Phc2 | 313038 | D4A0M3 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | phc2b | 394177 | F6P2R0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0035102 | PRC1 complex |
| GO:0003682 | chromatin binding |
| GO:0003677 | DNA binding |
| GO:0042393 | histone binding |
| GO:0008270 | zinc ion binding |
| GO:0045892 | negative regulation of transcription, DNA-templated |
| Pfam ID | Pfam Term |
|---|---|
| PF00536 | SAM_1 |