Gene: PHC2

Basic information

Tag Content
Uniprot ID I3LIR0
Entrez ID
Genbank protein ID HCZ89147.1
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000023966
Ensembl nucleotide ID ENSSSCG00000025344
Gene name Polyhomeotic homolog 2
Gene symbol PHC2
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MENELPPPHT SSSASVTSST SGVSSSSGGG NSSNSGGSGR PAGPQISVYS GIPDRQTVQV 60
IQQALHRQPS TAAQYLQQMY AAQQQHLMLQ TAALQQQHLS SAQLQSLAAV QQASLVANRQ 120
GSTSGSSASA QAPAQSSSIN LAASPAAAQL INRAQSVNSA AASGIAQQAV LLGNTSSPAL 180
TASQAQMYLR AQMAQPGNLV QVARSLGGTV PLSPQLIFTP TATVATVQPE LGTGSPARPP 240
TPAQVQNLTL RTQQTPTAAA SGPTPTQPVL PSLALKPTPG GSQPLPTPSQ GRNTAQGSPA 300
GAKPGISDSV MEPVKKGDGN GSVPGSLEGR AGLSRVVPAV ATHPLIAPAY AQLQPHQLLS 360
QSSSKHLQPQ FVIQQQQQQQ QQQQQQQQPP PQPSRPALQA QSHTQLASVP PSLALQPSSE 420
AHPVPLGPVT STLPLQCPSA NLHKPGSTQQ CHPPTPDAGP HNGYPEGLPH TPQRRFQHAS 480
AVILQLQPAS PVPQQCTPDD WKEVVPGEKS VPEMRSGPSP HQQAIVTALP GGLPVPKSPN 540
IQQSPAHETG QGIVHALTDL SSPGMTSGNG NSASSITGTA PQNGENKPPQ AIVKPQILTH 600
VIEGFVIQEG AEPFPVGRSS LLVGNLKKKY AQGFLPEKLP QQDHTTTTDS EMEEPYLQES 660
KEEGTPLKLK CELCGRVDFA YKFKRSKRFC SMACAKRYNV GCTKRVGLFH SDRSKLQKAG 720
ATTHNRRRAS KTSLPTLTKD TKKQPAGTVP LSVTAALQLT HSQEDSSRCS DNSSYEEPLS 780
PISASSSTSR RRQGQRDLEL PDMHMRDLVG MGHHFLPSEP TKWNVEDVYE FIRSLPGCQE 840
IAEEFRAQEI DGQALLLLKE DHLMSAMNIK LGPALKIYAR ISMLKDS 887

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPHC2537511E1BFG7Bos taurusPredictionMore>>
1:1 orthologPHC2487297J9P8A4Canis lupus familiarisPredictionMore>>
1:1 orthologPHC2A0A452F0Q9Capra hircusPredictionMore>>
1:1 orthologPHC21912Q8IXK0Homo sapiensPredictionMore>>
1:1 orthologPhc254383Q9QWH1CPOMus musculusPublicationMore>>
1:1 orthologPHC2456729H2PYL7Pan troglodytesPredictionMore>>
1:1 orthologPHC2I3LIR0Sus scrofaPredictionMore>>
1:1 orthologPHC2100351541G1T576Oryctolagus cuniculusPredictionMore>>
1:1 orthologPhc2313038D4A0M3Rattus norvegicusPredictionMore>>
1:1 orthologphc2b394177F6P2R0Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0000792 heterochromatin
GO:0005654 nucleoplasm
GO:0035102 PRC1 complex
GO:0042802 identical protein binding
GO:0008270 zinc ion binding
GO:0007283 spermatogenesis

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR001660 SAM
IPR013761 SAM/pointed_sf
IPR012313 Znf_FCS
IPR038603 Znf_FCS_sf

PROSITE

PROSITE ID PROSITE Term
PS50105 SAM_DOMAIN
PS51024 ZF_FCS

Pfam

Pfam ID Pfam Term
PF00536 SAM_1