| Tag | Content |
|---|---|
| Uniprot ID | F1MY63 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSBTAP00000009214 |
| Ensembl nucleotide ID | ENSBTAG00000007003 |
| Gene name | Thymidylate synthase |
| Gene symbol | TYMS |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPAAGSEPSR PPSPPGVQEQ SAEPRPPPPP HGELQYLGQI EHILRCGFRR DDRTGTGTLS 60 VFGMQARYNL RDEFPLLTTK RVFWKGVLEE LLWFIKGSTN AKELSSKGVK IWDANGSRDF 120 LDGLGFSDRA EGDLGPVYGF QWRHFGAEYK DMDSEYSGQG VDQLQKVIDT IKTNPNDRRI 180 ILCAWNPKDL PLMALPPCHA LCQFYVVNGE LSCQLYQRSG DMGLGVPFNI ASYALLTYMI 240 AHITDLKPGD FVHTLGDAHI YLNHIEPLKT QALMELRGQS SRSLDGDGQA GTSRWAPVAT 300 DTERDRCCEL QREPRPFPKL KILRKVETID DFQAEDFQIE GYNPHPTIKM EMAV 354 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TYMS | F1MY63 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | TYMS | A0A452DJS6 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | TYMS | 100060971 | F6TRC0 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | TYMS | 7298 | P04818 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Tyms | 22171 | P07607 | E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | TYMS | 740018 | G2HEY4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | TYMS | A0A287AFN2 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | TYMS | 100347408 | G1SVL8 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Tyms | 29261 | P45352 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | tyms | 81540 | Q6P045 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005739 | mitochondrion |
| GO:0004799 | thymidylate synthase activity |
| GO:0006231 | dTMP biosynthetic process |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00091 | THYMIDYLATE_SYNTHASE |
| Pfam ID | Pfam Term |
|---|---|
| PF00303 | Thymidylat_synt |