Gene: TYMS

Basic information

Tag Content
Uniprot ID G2HEY4; A0A2J8MPA5;
Entrez ID 740018
Genbank protein ID JAA44642.1; JAA10854.1; JAA26839.1; JAA14611.1; BAK62292.1;
Genbank nucleotide ID NM_001246582.1
Ensembl protein ID ENSPTRP00000016716
Ensembl nucleotide ID ENSPTRG00000009822
Gene name Fibronectin 1
Gene symbol TYMS
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MPVAGSELPR RPLPPAAQER DAEPRPPHGE LQYLGQIEHI LRCGVRKDDR TGTGTLSVFG 60
MQARYSLRDE FPLLTTKRVF WKGVLEELLW FIKGSTNAKE LSSKGVKIWD ANGSRDFLDS 120
LGFSTREEGD LGPVYGFQWR HFGAEYRDME SDYSGQGVDQ LQRVIDTIKS NPDDRRIIMC 180
AWNPRDLPLM ALPPCHALCQ FYVVNSELSC QLYQRSGDMG LGVPFNIASY ALLTYMIAHI 240
TGLKPGDFIH TLGDAHIYLN HIEPLKIQLQ REPRPFPKLK ILRKVEKIDD FKAEDFQIEG 300
YNPHPTIKME MAV 313

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTYMSF1MY63Bos taurusPredictionMore>>
1:1 orthologTYMSA0A452DJS6Capra hircusPredictionMore>>
1:1 orthologTYMS100060971F6TRC0Equus caballusPredictionMore>>
1:1 orthologTYMS7298P04818CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologTyms22171P07607E14.5Mus musculusPredictionMore>>
1:1 orthologTYMS740018G2HEY4Pan troglodytesPredictionMore>>
1:1 orthologTYMSA0A287AFN2Sus scrofaPredictionMore>>
1:1 orthologTYMS100347408G1SVL8Oryctolagus cuniculusPredictionMore>>
1:1 orthologTyms29261P45352Rattus norvegicusPredictionMore>>
1:1 orthologtyms81540Q6P045Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005829 cytosol
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005739 mitochondrion
GO:0005634 nucleus
GO:1990825 sequence-specific mRNA binding
GO:0004799 thymidylate synthase activity
GO:0000900 translation repressor activity, mRNA regulatory element binding
GO:0006231 dTMP biosynthetic process
GO:0046683 response to organophosphorus
GO:0035999 tetrahydrofolate interconversion

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR023451 Thymidate_synth/dCMP_Mease
IPR036926 Thymidate_synth/dCMP_Mease_sf
IPR000398 Thymidylate_synthase
IPR020940 Thymidylate_synthase_AS

PROSITE

PROSITE ID PROSITE Term
PS00091 THYMIDYLATE_SYNTHASE

Pfam

Pfam ID Pfam Term
PF00303 Thymidylat_synt