Gene: TYMS

Basic information

Tag Content
Uniprot ID G1SVL8
Entrez ID 100347408
Genbank protein ID
Genbank nucleotide ID XM_002713438.3
Ensembl protein ID ENSOCUP00000007483
Ensembl nucleotide ID ENSOCUG00000008667
Gene name Thymidylate synthetase
Gene symbol TYMS
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MPAAGSELPS PPTAQEQGAE ARPPHGELQY LGQIEHILRC GFRKEDRTGT GTLSVFGMQA 60
RYSLRDEFPL LTTKRVFWKG VLEELLWFIK GSTNAKELSS KGVKIWDANA SRDFLDSLGF 120
STRQEGDLGP VYGFQWRHFG AEYKDKDSDY SGQGVDQLQK VIDTIKTNPD DRRIIMCAWN 180
PKDLPLMALP PCHALCQFYV VNGELSCQLY QRSGDMGLGV PFNIASYALL TYMIAHVTGL 240
KPGDFVHTLG DAHIYLNHIE PLKTQLQREP RPFPKLKILR KVETIDDFKA EDFQLEGYNP 300
HPTIKMEMAV

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTYMSF1MY63Bos taurusPredictionMore>>
1:1 orthologTYMSA0A452DJS6Capra hircusPredictionMore>>
1:1 orthologTYMS100060971F6TRC0Equus caballusPredictionMore>>
1:1 orthologTYMS7298P04818CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologTyms22171P07607E14.5Mus musculusPredictionMore>>
1:1 orthologTYMS740018G2HEY4Pan troglodytesPredictionMore>>
1:1 orthologTYMSA0A287AFN2Sus scrofaPredictionMore>>
1:1 orthologTYMS100347408G1SVL8Oryctolagus cuniculusPredictionMore>>
1:1 orthologTyms29261P45352Rattus norvegicusPredictionMore>>
1:1 orthologtyms81540Q6P045Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0004799 thymidylate synthase activity
GO:0006231 dTMP biosynthetic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR023451 Thymidate_synth/dCMP_Mease
IPR036926 Thymidate_synth/dCMP_Mease_sf
IPR000398 Thymidylate_synthase
IPR020940 Thymidylate_synthase_AS

PROSITE

PROSITE ID PROSITE Term
PS00091 THYMIDYLATE_SYNTHASE

Pfam

Pfam ID Pfam Term
PF00303 Thymidylat_synt