| Tag | Content |
|---|---|
| Uniprot ID | F1PF09 |
| Entrez ID | 480677 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_537796.5 |
| Ensembl protein ID | ENSCAFP00000029108 |
| Ensembl nucleotide ID | ENSCAFG00000019672 |
| Gene name | Peptidase, mitochondrial processing alpha subunit |
| Gene symbol | PMPCA |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAAMVVAAAR VLLRGSGSWR CSRLRSGAPS RRQFSGGGAY PHVPLSSPLP GVPEPVFATV 60 DGQEKFETKV TTLDNGLRVA SQNKFGQFCT VGILINSGSR YEAKYLSGIA HFLEKLAFSS 120 TDRFESKDEI LLTLEKHGGI CDCQTSRDTT MYAVSADSKG LDTVVGLLAD VVLHPRLTDK 180 EIEMTRMAVQ FELEDLNMRP DPEPLLTEMI HEAAYRENTV GLHRFCPTEN IAKIDREVLH 240 SYLRNYYTPD RMVLAGVGVE HEHLVECARK YLLGTQPAWG CEKAVDVDRS VAQYTGGVVK 300 LERDMSNVSL GPAPFPELTH IMIGLESCSF LEEDFIPFAV LNMMMGGGGS FSAGGPGKGM 360 FTRLYLNVLN RHHWMYNATS YHHSYEDTGL LCVHASADPR QVREMVEILT KEFILMAGTV 420 DVVELERAKT QLMSMLMMNL ESRPVIFEDV GRQVLATRSR KLPHELCALI RSVKPEDIRR 480 VASQMLCRKP AVAALGDLSH LPAYEHIQAA LSSRDGRLPR TYRLFR 526 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PMPCA | 767847 | Q0P5M8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PMPCA | 480677 | F1PF09 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PMPCA | 102171796 | A0A452EEL9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PMPCA | 23203 | Q10713 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pmpca | 66865 | Q9DC61 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PMPCA | H2QY64 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PMPCA | A0A5G2Q8L1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Pmpca | 296588 | Q68FX8 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pmpca | A0A0R4IFK9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005743 | mitochondrial inner membrane |
| GO:0017087 | mitochondrial processing peptidase complex |
| GO:0005739 | mitochondrion |
| GO:0046872 | metal ion binding |
| GO:0004222 | metalloendopeptidase activity |
| GO:0006627 | protein processing involved in protein targeting to mitochondrion |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00143 | INSULINASE |