| Tag | Content |
|---|---|
| Uniprot ID | Q68FX8 |
| Entrez ID | 296588 |
| Genbank protein ID | EDL93500.1; AAH79004.1; |
| Genbank nucleotide ID | NM_001003673.1 |
| Ensembl protein ID | ENSRNOP00000037642 |
| Ensembl nucleotide ID | ENSRNOG00000026775 |
| Gene name | Mitochondrial-processing peptidase subunit alpha |
| Gene symbol | Pmpca |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MATAVWAAAR LLRGSAALCA RPKFGSPAHR RFSSGATYPN IPLSSPLPGV PKPIFATVDG 60 QEKFETKVTT LDNGLRVASQ NKFGQFCTLG ILINSGSRYE AKYLSGIAHF LEKLAFSSTA 120 RFDSKDEILL TLEKHGGICD CQTSRDTTMY AVSADSKGLD TVVGLLADVV LHPRLTDEEI 180 EMTRMAVQFE LEDLNMRPDP EPLLTEMIHE AAFRENTVGL HRFCPVENIG KIDREVLHSY 240 LKNYYTPDRM VLAGVGVEHE HLVECARKYL LGVQPAWGAP GAVDVDSSVA QYTGGIIKVE 300 RDMSNVSLGP TPIPELTHIM VGLESCSFLE EDFIPFAVLN MMMGGGGSFS AGGPGKGMFS 360 RLYLNVLNRH HWMYNATSYH HSYEDTGLLC IHASADPRQV REMVEIITKE FILMGRTVDL 420 VELERAKTQL MSMLMMNLES RPVIFEDVGR QVLATHSRKL PHELCTLIRN VKPEDIKRVA 480 SKMLRGKPAV AALGDLTDLP TYEHIQAALS SRDGRLPRTY RLFR 524 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PMPCA | 767847 | Q0P5M8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PMPCA | 480677 | F1PF09 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PMPCA | 102171796 | A0A452EEL9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PMPCA | 23203 | Q10713 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pmpca | 66865 | Q9DC61 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PMPCA | H2QY64 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PMPCA | A0A5G2Q8L1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Pmpca | 296588 | Q68FX8 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pmpca | A0A0R4IFK9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005743 | mitochondrial inner membrane |
| GO:0046872 | metal ion binding |
| GO:0004222 | metalloendopeptidase activity |
| GO:0006627 | protein processing involved in protein targeting to mitochondrion |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00143 | INSULINASE |