| Tag | Content |
|---|---|
| Uniprot ID | H2QY64 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000036911 |
| Ensembl nucleotide ID | ENSPTRG00000021556 |
| Gene name | Peptidase, mitochondrial processing alpha subunit |
| Gene symbol | PMPCA |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAAVVLAATR LLRGSGSWGC SRLRFGPPAY RRFSSGGAYP NIPLSSPLPG VPKPVFATVD 60 GQEKFETKVT TLDNGLRVAS QNKFGQFCTV GILINSGSRY EAKYLSGIAH FLEKLAFSST 120 ARFDSKDEIL LTLEKHGGIC DCQTSRDTTM YAVSADSKGL DTVVGLLADV VLQPRLTDEE 180 VEMTRMAVQF ELEDLNLRPD PEPLLTEMIH EAAYRENTVG LHRFCPTENI AKINREVLHS 240 YLRNYYTPDR MVLAGVGVEH EHLVDCARKY LLGVQPAWGS AEAVDIDRSV AQYTGGIAKL 300 ERDMSNVSLG PTPIPELTHI MVGLESCSFL VSPVWPAQPA LPSVPGIRQR SSCGVVPIHS 360 VTLASSRHHW VYNYEDTAPP CIHCPENHHK EFILMGGTVD AVELERAKTQ LTSMLMMNLE 420 SRPVIFEDVG RQVLATRSRK LPHELCTLIR NVKPEDVKRV ASKMLRGKPA VAALGDLTDL 480 PTYEHIQTAL SSKDGRLPRT YRLFR 505 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PMPCA | 767847 | Q0P5M8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PMPCA | 480677 | F1PF09 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PMPCA | 102171796 | A0A452EEL9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PMPCA | 23203 | Q10713 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pmpca | 66865 | Q9DC61 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PMPCA | H2QY64 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PMPCA | A0A5G2Q8L1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Pmpca | 296588 | Q68FX8 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pmpca | A0A0R4IFK9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005739 | mitochondrion |
| GO:0046872 | metal ion binding |
| GO:0004222 | metalloendopeptidase activity |
| GO:0006627 | protein processing involved in protein targeting to mitochondrion |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00143 | INSULINASE |