| Tag | Content |
|---|---|
| Uniprot ID | F1PKX3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_535876.5 |
| Ensembl protein ID | ENSCAFP00000013985 |
| Ensembl nucleotide ID | ENSCAFG00000009509 |
| Gene name | Coagulation factor XIII A chain |
| Gene symbol | F13A1 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSETSGPAFG GRRALPRNAS NAAEDDLPTV ELQGGPVPRG VNLQDYLHVT NIHLFKERWD 60 TNKVDHHTDK YENNKLIVRR GQSFFIQIDF NRPYDPRRDL FRVEYVIGRY PQENKGTYIP 120 VPIVPELQRG KWGAKVIMRE NRSVRLSIQS SPECIVGKFR MYVAVWTPYG ILRTSRNPET 180 DTYILFNPWC EEDAVYLDGD KEREEYVLND IGVIFYGDFN DIKSRSWSYG QFEDGILDAC 240 LYVMDKAQMD LSGRGNPIKV SRVGSAMVNA KDDEGVLVGS WDNIYAYGVP PSAWTGSVDI 300 LLEYQSTKSP VRYGQCWVFA GVFNTFLRCL GIPARVITNY FSAHDNDANL QMDIFLEEDG 360 NVNSKLTKDS VWNYHCWNEA WMTRPDLPVG FGGWQAVDST PQENSDGMYR CGPASVQAIK 420 HGHICFQFDA PFVFAEVNSD LIYITAKKDG THVVETVDTT HIGKLIVTKE VGGDGIKDIT 480 DTYKFQEGQE EERLALETAL MYGAKKPLNI EGILKPRSDV DMNFDVENAV LGRDFKLTIT 540 FQNNSPRRYT LLAYLSGNIV FYTGVSKTEF KKETFEVTLE PLSFKREEVL IRAGEYMGQL 600 LEQAYLHFFV TARVNESKDI LAKQKSTVLT IPQLIIKVRG AKMVGSDMVV TVEFTNPLKE 660 TLRNVWIHLD GPGVIKPMRK MFREIQPSAT IQWEEVCRPW VSGPRKLIAS MTSDSLRHVY 720 GELNLQIQRR PSA 733 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | F13A1 | F1PKX3 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | F13A1 | 102169238 | A0A452FF40 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | F13A1 | 2162 | P00488 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | F13a1 | 74145 | Q8BH61 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | F13A1 | 462413 | H2QS92 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | F13A1 | 100153504 | K7GQL2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | F13a1 | 60327 | G3V811 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | f13a1b | F1R1R7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0046872 | metal ion binding |
| GO:0003810 | protein-glutamine gamma-glutamyltransferase activity |
| GO:0072378 | blood coagulation, fibrin clot formation |
| GO:0018149 | peptide cross-linking |
| InterPro ID | InterPro Term |
|---|---|
| IPR034810 | Factor_XIII_A |
| IPR013783 | Ig-like_fold |
| IPR014756 | Ig_E-set |
| IPR038765 | Papain-like_cys_pep_sf |
| IPR002931 | Transglutaminase-like |
| IPR036985 | Transglutaminase-like_sf |
| IPR023608 | Transglutaminase_animal |
| IPR013808 | Transglutaminase_AS |
| IPR008958 | Transglutaminase_C |
| IPR036238 | Transglutaminase_C_sf |
| IPR001102 | Transglutaminase_N |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00547 | TRANSGLUTAMINASES |