| Tag | Content |
|---|---|
| Uniprot ID | H2QS92; A0A2J8MTU6; |
| Entrez ID | 462413 |
| Genbank protein ID | JAA39992.1 |
| Genbank nucleotide ID | XM_009450449.2 |
| Ensembl protein ID | ENSPTRP00000030210 |
| Ensembl nucleotide ID | ENSPTRG00000017694 |
| Gene name | Coagulation factor XIII A chain |
| Gene symbol | F13A1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSETSRTAFG GRRAVPPNNS NAAEDDLPTV ELQGVVPRGV NLQEFLNVTS VHLFKERWDT 60 NKVDHHTDKY ENNKLIVRRG QSFYVQIDFN RPYDPRRDLF RVEYVIGRYP QENKGTYIPV 120 PIVSELQSGK WGAKIVMRED RSVRLSIQSS PKCIVGKFRM YVAVWTPYGV LRTSRNPETD 180 TYILFNPWCE DDAVYLDNEK EREEYVLNDI GVIFYGEVND IKTRSWSYGQ FEDGILDTCL 240 YVMDRAQMDL SGRGNPIKVS RVGSAMVNAK DDEGVLVGSW DNIYAYGVPP SAWTGSVDIL 300 LEYRSSENPV RYGQCWVFAG VFNTFLRCLG IPARIVTNYF SAHDNDANLQ MDIFLEEDGN 360 VNSKLTKDSV WNYHCWNEAW MTRPDLPVGF GGWQAVDSTP QENSDGMYRC GPASVQAIKH 420 GHVCFQFDAP FVFAEVNSDL IYITAKKDGT HVVENVDATH IGKLIVTKQI GGDGMMDITD 480 TYKFQEGQEE ERLALETALM YGAKKPLNTE GVVKSRSNVD MDFEVENAVL GKDFKLSITF 540 RNNSHNRYTI TAYLSANITF YTGVPKAEFK KETFDVTLEP LSFKKEAVLI QAGEYMGQLL 600 EQASLHFFVT ARINETRDVL AKQKSTVLTI PEIIIKVRGT QVVGSDMTVT VEFTNPLKET 660 LRNVWIHLDG PGITRPMKKM FREIRPNSTV QWEEVCRPWV SGHRKLIASM SSDSLRHVYG 720 ELDVQIQRRP SM 732 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | F13A1 | F1PKX3 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | F13A1 | 102169238 | A0A452FF40 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | F13A1 | 2162 | P00488 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | F13a1 | 74145 | Q8BH61 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | F13A1 | 462413 | H2QS92 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | F13A1 | 100153504 | K7GQL2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | F13a1 | 60327 | G3V811 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | f13a1b | F1R1R7 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0046872 | metal ion binding |
| GO:0003810 | protein-glutamine gamma-glutamyltransferase activity |
| GO:0072378 | blood coagulation, fibrin clot formation |
| GO:0018149 | peptide cross-linking |
| InterPro ID | InterPro Term |
|---|---|
| IPR034810 | Factor_XIII_A |
| IPR013783 | Ig-like_fold |
| IPR014756 | Ig_E-set |
| IPR038765 | Papain-like_cys_pep_sf |
| IPR002931 | Transglutaminase-like |
| IPR036985 | Transglutaminase-like_sf |
| IPR023608 | Transglutaminase_animal |
| IPR013808 | Transglutaminase_AS |
| IPR008958 | Transglutaminase_C |
| IPR036238 | Transglutaminase_C_sf |
| IPR001102 | Transglutaminase_N |
| PROSITE ID | PROSITE Term |
|---|---|
| PS00547 | TRANSGLUTAMINASES |